Urinary Uric Acid Creatinine ratio useful marker of morbidity and mortality of preterm infants
Perinatal asphyxia is one of the main causes of preterm infant mortality. Some studies have shown that The Urinary Uric Acid / Cr (UUA/Cr) ratio may be used as an additional marker for perinatal asphyxia. However, urinary uric Acid / Cr ratio in the first 24 h after birth in preterm neonates who underwent intubation, nasal continuous positive airway pressure or cardiopulmonary resuscitation was higher than healthy neonates, reports a study.
The research is published in the BMC Pediatrics.
The present case–control study was carried on 102 preterm newborn infants with gestational age of 30 weeks to 33 weeks and 6 days admitted in the neonatal intensive care unit. The case group, consisted of 51 premature neonates with a history of intubation, cardiopulmonary resuscitation, mechanical ventilation and Nasal continuous positive airway pressure (NCPAP) at birth, were compared with 51 matched neonates.
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