Delayed Treatment with Inhaled Corticosteroids Affects Lung Function in Asthma, finds study
Researchers have found in a new study that patients with severe asthma beginning inhaled corticosteroid therapy (ICS) after decades delay exhibit different lung function trajectories. ICS is still considered the first-line treatment for asthma, but its long-standing effects on the lung function decline remain uncertain, especially after delayed initiation. This research was an examination of lung function decline, bearing in mind the predictors of FEV1 modifications and exacerbations in patients with previously untreated severe asthma. The study was conducted by Pca Almeida and colleagues which was published in the Journal of Asthma.
A ten-year-long observational study of 184 patients with asthma following regular inhaled corticosteroid (ICS) treatment was conducted. Most patients were female (84%) and over 50 years old. After a median of 30 years on regular ICS, they began. The lung function decline was assessed using two baseline options: (i) FEV1 after one year of regular treatment (V1) and (ii) the best FEV1 of any recorded previously before the final visit. This study aims to compare lung function outlines during the overall follow-up time with respect to the baseline and teeter and recognize predictors of further FEV1 decline and exacerbations.
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