intranasal corticosteroids not recommended for most children with OSA: study
According to a recent study published in The Chest, treatment with intranasal corticosteroids is ineffective in children with obstructive sleep apnea syndrome.
Obstructive sleep apnea occurs when the muscles in your throat that support soft tissues such as the tongue and soft palate temporarily relax. When these muscles relax, your airway narrows or closes and breathing is momentarily interrupted.
Intranasal corticosteroids (INCS) are often used to treat obstructive sleep apnea syndrome (OSAS) in children. However, their effectiveness has not been rigorously tested.
In this randomised, double-blind, placebo-controlled study, children aged 5 to 12 years (n=134) with obstructive sleep apnea syndrome were randomised 2:1 to 3 months of intranasal corticosteroids or placebo. Children in the Intranasal corticosteroids arm were then re-randomized to 9 months of Intranasal corticosteroids or placebo. Polysomnography, symptoms, and neurobehavioral findings were measured at baseline, 3, and 12 months. The primary outcome was the obstructive apnea-hypopnea index (OAHI) change at 3 months, available for 122 children. The secondary outcome was the obstructive apnea-hypopnea index change at 12 months, available for 70 children.
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