Plasma fibrinogen levels increase pulmonary infection risk among spinal cord injury patients: Study
A recent study published in the journal of BMC Pulmonary Medicine showed that elevated plasma fibrinogen levels dramatically raise the risk of pulmonary infections (PI) in individuals with spinal cord injury (SCI). Pulmonary infections are a major source of morbidity and mortality in this group and were far more likely to occur in patients with spinal cord injury. Due in part to respiratory myasthenia, which impairs lung function and coughing capacity and is frequent following SCI, such infections are more dangerous for individuals with SCI. Respiratory dysfunction appeared as one of the most severe and potentially deadly effects for individuals with cervical SCI, whereas pneumonia was a prevalent and major complication.
Aspiration pneumonia and mechanical airway blockage are two more severe consequences that can arise in individuals with traumatic cervical SCI who have swallowing difficulty. Pulmonary infections are more common in patients with spinal cord injuries, and plasma fibrinogen levels may be a risk factor for PI in and of itself. Thus, to clarify the relationship between plasma fibrinogen levels and the incidence of PI in SCI patients, Jinlong Zhang and her colleagues carried out this investigation.
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