Sugary Western diet ups breast cancer risk: study

"The current study investigated the impact of dietary sugar on mammary gland tumour development in multiple mouse models, along with mechanisms that may be involved," study co-author Lorenzo Cohen, professor at University of Texas MD Anderson Cancer Centre.

"We determined that it was specifically fructose, in table sugar and high-fructose corn syrup, ubiquitous within our food system, which was responsible for facilitating lung metastasis and 12-HETE (a fatty acid) production in breast tumours," Cohen said.

The research team conducted different studies in which mice were randomised to different diet groups.

At six months of age, 30 percent of mice on a starch-control diet had measurable tumours, whereas 50 to 58 percent of the mice on sucrose-enriched diets had developed mammary tumours.

The study also showed that numbers of lung metastases were significantly higher in mice on a sucrose - or a fructose-enriched diet, versus mice on a starch-control diet.