Antisperm Antibodies After Vasectomy Reversal Not Linked to Pregnancy Rates or contraception method: Study

Key Findings:

• A total of 204 patients were included in the study, with a median age of 40 years and a median obstruction interval of 7.3 years.

• 85 patients (42%) had low ASA levels (<50%), while 119 (58%) had high ASA levels (≥50%).

• Among the patients with low ASA levels, 70% achieved pregnancy, with 59% resulting from spontaneous conception.

• For patients with high ASA levels, 75% achieved pregnancy, with 40% resulting from spontaneous conception.

• Fisher's exact test p-value for the difference in pregnancy rates based on ASA levels was 0.2, indicating no significant association.

The study found no association between ASA levels and pregnancy rates or method of conception following vasectomy reversal. These findings provide valuable insights for patient counseling, alleviating concerns regarding the potential impact of ASAs on fertility outcomes post-reversal. As such, clinicians can better inform patients about their likelihood of achieving pregnancy after vasectomy reversal, regardless of ASA levels.

Reference:

Nam, C. S., Tooke, B. P., Strasser, O., Hameed, M. A., Chinnusamy, S., Van Til, M., Daignault-Newton, S., & Dupree, J. M. Antisperm antibody levels after vasectomy reversal are not associated with pregnancy rates or method of conception. Urology,2024. https://doi.org/10.1016/j.urology.2024.02.028