Blood tests not helpful for screening metabolic disorders in kidney stone disease, Study says
Recent research published in the BJU International Journal reveals that Use of additional blood tests to screen for metabolic disorders is not cost-effective and may provide false reassurance that metabolic abnormalities are not present.
However, a full metabolic assessment with 24-h urine collection should be undertaken in recurrent stone formers and in those at high risk of future stone disease to identify potentially treatable metabolic abnormalities, explained Katie S Eyre and colleagues from the Department of Urology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
The authors carried out this study with the objective to determine the clinical utility of blood tests as a screening tool for metabolic abnormalities in patients with kidney stone disease.
Clinical and biochemical data from 709 patients attending the Oxford University Hospitals NHS Foundation Trust for assessment and treatment of kidney stones were prospectively collected. Data were analyzed to determine the utility of serum calcium, parathyroid hormone (PTH), urate, chloride, bicarbonate, potassium and phosphate assays in screening for primary hyperparathyroidism, normocalcaemic hyperparathyroidism, hyperuricosuria, distal renal tubular acidosis (dRTA) and hypercalciuria.
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