Enzalutamide effective in patients with metastatic Hormone-Sensitive Prostate Cancer
Enzalutamide therapy is beneficial in patients with Metastatic Hormone-Sensitive Prostate Cancer, according to a recent study published in the Journal of Clinical Oncology
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In primary analysis, enzalutamide plus androgen deprivation therapy (ADT) improved radiographic progression-free survival (rPFS) in patients with metastatic hormone-sensitive prostate cancer (mHSPC); however, overall survival data were immature. In the phase III, double-blind, global ARCHES trial 1,150 patients with mHSPC were randomly assigned 1:1 to enzalutamide (160 mg once daily) plus ADT or placebo plus ADT, stratified by disease volume and prior docetaxel use.
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