Percutaneous tibial nerve stimulations effective in refractory OAB: Study

The study was a prospective randomized controlled trial comparing the efficacy of percutaneous tibial nerve stimulation versus sham for a shortened 6 week protocol of treatment in management of refractory OAB in non-neurogenic adult patients.

For the study design, a total of 50 adults with refractory overactive bladder symptoms were randomized 1:1 to 6 weeks of treatment with weekly percutaneous tibial nerve stimulation or sham therapy. Overactive bladder symptom scores as well as 3-day voiding diaries were completed at baseline and at 7th week, 3rd and 6th month.

Data analysis revealed the following facts.

• The 7th week, 3 rd and 6 th month symptom scores assessment for overall bladder symptoms demonstrated that percutaneous tibial nerve stimulation patients achieved statistically significant improvement in bladder symptoms with 52% reporting moderately improved responses compared to non-response of sham patients from baseline (p = 0.001).
• Voiding diary parameters after 6 weeks of therapy showed that PTNS patients had statistically significant improvements in frequency, voided volume and urgency urinary incontinence episodes compared to sham.
• No serious device related adverse events or malfunctions were reported.

For full article follow the link: https://doi.org/10.1016/S2666-1683(20)33125-6

Primary source: European Urology Open Science