Pesticides exposure decreased male fertility: Epidemiologic study

2. Sperm motility, total sperm count, and sperm morphology were the most frequently affected variables, but a decrease in ejaculate volume and concentration happened in a few instances.

3. Organochlorines and organophosphates were linked to a noticeable decline in semen quality.

4. In addition, exposure to pesticides, particularly pyrethroids, was typically linked to greater DNA fragmentation indices and chromosome aneuploidies.

In conclusion, the effects of exposure to pesticides on human semen parameters were summarized in the current study, and it was discovered that there was a negative influence on sperm total count, motility, and normal morphology as well as damage to DNA integrity. Rather than dose, these effects appear to be primarily connected with exposure period. To corroborate these results and to bolster the evidence for causation, future prospective studies with the right approach to adjust for systematic uncertainty are necessary because present knowledge almost exclusively relies on cross-sectional evaluations.

Reference: 

Giulioni, C., Maurizi, V., Castellani, D., Scarcella, S., Skrami, E., Balercia, G., & Galosi, A. B. (2022). The environmental and occupational influence of pesticides on male fertility: A systematic review of human studies. In Andrology. Wiley. https://doi.org/10.1111/andr.13228