Plant-based diets may be associated with lower risk of aggressive prostate cancer

Written By :  Dr. Shravani Dali
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2023-02-02 04:15 GMT   |   Update On 2023-02-02 09:41 GMT

Plant-based diets may be associated with a lower risk of aggressive prostate cancer suggests a recent study published in The American Journal of Clinical Nutrition

Plant-based diets are associated with multiple health benefits and a favorable environmental impact. For prostate cancer, previous studies suggest a beneficial role of specific plant-based foods (e.g., tomatoes) and a potentially harmful role of specific animal-based foods (e.g., meat, dairy). However, less is known about plant-based dietary patterns.

Researchers sought to examine the relation between plant-based diet indices and prostate cancer risk, including clinically relevant disease.
This prospective cohort study included 47,239 men in the Health Professionals Follow-Up Study (1986–2014). Overall and healthful plant-based diet indices were calculated from FFQs. Cox proportional hazards models were used to estimate HRs and 95% CIs to examine the risk of incident prostate cancer (total and by clinical category), among men ages <65 and ≥65 y.
Results
• Of the 47,239 men, 6655 men were diagnosed with prostate cancer over follow-up, including 515 with advanced-stage disease at diagnosis, 956 with lethal disease (metastasis or death), and 806 prostate cancer deaths.
• Greater overall plant-based consumption was associated with a significantly lower risk of fatal prostate cancer
• In men aged <65, a higher plant-based diet index was associated with a lower risk of advanced, lethal, and fatal prostate cancer.
• Moreover, greater consumption of a healthful plant-based diet was associated with lower risks of total and lethal prostate cancer
There were no associations between overall or healthful plant-based diet indices with prostate cancer among men ≥65 y.
• Fewer than 1% of participants followed a strict vegetarian or vegan diet.

This prospective study provides supportive evidence that greater consumption of healthful plant-based foods is associated with a lower risk of aggressive forms of prostate cancer, with stronger benefit among men aged <65 y.

Reference:

Stacy Loeb, Benjamin C Fu, Scott R Bauer, Claire H Pernar, June M Chan, Erin L Van Blarigan, Edward L Giovannucci, Stacey A Kenfield, Lorelei A Mucci,

Association of plant-based diet index with prostate cancer risk,The American Journal of Clinical Nutrition,Volume 115, Issue 3,2022,Pages 662-670,ISSN 0002-9165,https://doi.org/10.1093/ajcn/nqab365.

Keywords:

Plant-based, diets, associated, lower, risk, aggressive, prostate cancer, The American Journal of Clinical Nutrition, Stacy Loeb, Benjamin C Fu, Scott R Bauer, Claire H Pernar, June M Chan, Erin L Van Blarigan, Edward L Giovannucci, Stacey A Kenfield, Lorelei A Mucci

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Article Source : The American Journal of Clinical Nutrition

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