Sleep disturbance and depression linked to worse QoL among patients with OAB
Overactive bladder (OAB) can have a negative impact on health-related quality of life (HRQoL) and treatment adherence, but the exact nature of their relationship is unclear.
A study published in Neurology and Urodynamics concluded that Among individuals with OAB, Sleep Disturbance, Fatigue, and Depression scores were in line with general population reference values. Based on insights from the subgroup analysis, those taking antidepressants had a lower quality of life (health-related), substantially impacting adherence to their medication, indicating the need for proper assessment and management of depression in this population.
The present study characterized Sleep Disturbance, Depression, Fatigue, and patient-reported medication adherence among adults with overactive bladder in the US.
This study was a descriptive, observational one. Patients completed patient-reported outcome (PRO) measures on their urinary symptoms, anxiety, depression, fatigue, sleep quality, and medication adherence. The researchers then compared these scores across different subgroups based on age, sex, BMI, and medication (sleep and antidepressant) use. They performed exploratory analyses.
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