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  • Atrial fibrillation...

Atrial fibrillation and adipokines: A pathophysiological perspective

Dr. Kamal Kant KohliWritten by Dr. Kamal Kant Kohli Published On 2024-06-16T20:30:32+05:30  |  Updated On 16 Jun 2024 8:30 PM IST
Atrial fibrillation and adipokines: A pathophysiological perspective
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Announcing a new article publication for Cardiovascular Innovations and Applications journal. Atrial fibrillation (AF) is a prevalent cardiac arrhythmia characterized by irregular and frequently rapid electrical activity in the atria. Adipokines are bioactive molecules that are secreted by adipose tissue, and exert diverse effects on health and disease.

Obesity is a complex condition influenced by multiple interconnected factors, and the specific mechanisms linking obesity to AF may vary among individuals. Obesity contributes to the development of atrial arrhythmia. Moreover, obesity plays major roles in the pathophysiology of AF and its associated complications by inducing systemic changes, including altered hemodynamics, heightened sympathetic tone, and a persistent low-grade inflammatory state.

Although the associations between overweight or obesity and elevated risk of AF have been established, the underlying mechanisms remain incompletely characterized. This article highlights the pathophysiological aspects of adipokines, such as Angiopoietin-like protein 2, Fibroblast growth factor 21, Lipocalin, Vaspin, Visfatin, and Nesfatin-1, in AF and concludes that adipokines play major roles in AF pathogenesis.

Reference:

Saira Rafaqat, Iqra Noshair and Mehnaz Arif et al. Atrial Fibrillation and Adipokines: A Pathophysiological Perspective. CVIA. 2024. Vol. 9(1). DOI: 10.15212/CVIA.2024.0035.

Cardiovascular Innovations and ApplicationsAtrial fibrillationadipokinesObesity
Source : Cardiovascular Innovations and Applications
Dr. Kamal Kant Kohli
Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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