- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
High urea levels associated with increased left ventricular hypertrophy risk, suggests study
Wantai Dang and team from the First Affiliated Hospital of Chengdu Medical College found the potential associations of echocardiographic parameters with cardiovascular health in gout patients. The findings of the study were published in Frontiers in Physiology.
This study was conducted from November 2019 to December 2020 to provide a clinical foundation for early diagnosis and intervention in cardiovascular diseases among gout patients.
The study included gout patients from outpatient and inpatient departments and utilized two-dimensional speckle tracking analysis. Spearman correlation tests were also employed to dissect the relationships between laboratory indicators and echocardiographic parameters.
Multivariate logistic regression found elevated fasting plasma glucose which emerged as a risk factor for the reduction in the absolute value of global longitudinal strain (GLS). This emphasized its important role in subclinical left ventricular myocardial dysfunction. Urea marker was revealed as a risk factor for the absolute reduction in global circumferential strain (GCS). Age and hypertension were identified to be contributors that increased E/Em and marked an association with potential cardiovascular implications.
The study showed that heightened urea levels correlated with an increased risk of left ventricular hypertrophy (LVH) and an enlargement of left atrial volume index (LAVI) by underlining the systemic impact of gout on cardiac health.
This comprehensive study establishes a critical link between gout and subclinical left ventricular dysfunction and also identifies specific risk factors. Elevated urea and fasting plasma glucose levels were highlighted as significant contributors by laying the groundwork for early diagnosis and targeted treatment strategies in clinical practice. The outcomes of this study unravel the intricate interplay between metabolic disorders and cardiovascular health and takes us a step closer toward a more accurate understanding and enhanced care for patients with gout.
Source:
Dang, W., Luo, D., Hu, J., Luo, H., Xu, X., & Liu, J. (2023). Analysis of risk factors for changes of left ventricular function indexes in Chinese patients with gout by echocardiography. Frontiers in Physiology, 14. https://doi.org/10.3389/fphys.2023.1280178
Neuroscience Masters graduate
Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751