Optimal control of blood sugar, BP, and AF reduces risk of heart failure: Study

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2020-09-08T11:30:14+05:30 | Updated On 8 Sept 2020 3:48 PM IST

China: Conservative blood sugar control, and rhythm control of atrial fibrillation (AF), in addition to intensive BP control, are crucial for delaying the progression of heart failure in type 2 diabetes, hypertension, and AF patients, according to a recent study. The study is published in the Internal Medicine Journal.

Atrial fibrillation, hypertension and type 2 diabetes mellitus (T2DM) are risk factors for heart failure with preserved ejection fraction (HFpEF). This study by Li Fan, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China, and colleagues examined the effects of the simultaneous control of all 3 conditions on the new‐onset HFpEF in this population.

The study involved 552 patients with T2DM, hypertension and AF sans clinical signs or symptoms of heart failure. They were followed for 5 years to examine the effects of blood sugar control (hemoglobin A1c: < 7.0%, 7.0%‐8.0% and > 8.0%), blood pressure (BP) control (systolic BP: <120 mmHg, 120‐140 mmHg and >140 mmHg) or rhythm versus rate control for AF on new‐onset HFpEF.

Key findings of the study include:

With a follow‐up of 5 years, the new‐onset HFpEF occurred in 62 of 552 enrolled participants.
Among the different control level for diabetes, hypertension and AF, the intensive blood glucose (BG) control, poor BP control and rate control of AF had the highest risk of new‐onset HFpEF, and the conservative BG control, intensive BP control and rhythm control of AF had the lowest risk of new‐onset HFpEF.
Multivariable cox regression analysis showed that both poor BP control (HR: 1.421) and rate control of AF (HR: 1.362) were independently associated with the development of new‐onset HFpEF.

Our findings demonstrate that besides intensive BP control, rhythm control of AF and conservative blood sugar control are crucial factors for delaying the progression of HFpEF among patients with AF, T2DM, and hypertension.

The study, "Optimal management of blood glucose, blood pressure and atrial fibrillation to reduce the risk of heart failure with preserved ejection fraction," is published in the journal Internal Medicine Journal.

DOI: https://doi.org/10.1111/imj.15006

Internal Medicine Journalblood pressureblood sugartype 2 diabetesheart failure with preserved ejection fractionatrial fibrillation

Source : Internal Medicine Journal

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751