Quercetin supplementation lowers BP in normotensive and hypertensive patients: Study

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-08-11T20:00:14+05:30 | Updated On 11 Aug 2022 8:00 PM IST

Poland: Results from a meta-analysis published in Current Problems in Cardiology suggest that quercetin supplementation lowers blood pressure (BP) in normotensive and (pre)hypertensive patients.

High blood pressure (BP) is considered a recognized risk factor for cardiovascular diseases (CVDs) according to the American Heart Association. Hypertension is a widespread condition and there is a need for effective strategies for its treatment and prevention. Recent findings have suggested flavonoids due to their anti-inflammatory potential, with quercetin as one of the most important them, could be useful in hypertension prevention or treatment as it is the most naturally abundant and well-investigated flavonol already linked with a cardioprotective potential and reduced risk of vascular disease in studies conducted in vitro or on animal models.

Against the above background, Joanna Popiolek-Kalisz and Emilia Fornal from Poland aimed to summarize data focused on quercetin's impact on systolic BP (SBP) and diastolic BP (DBP). They revised the findings from previous meta-analyses in the context of newly published results coming from randomized control trials (RCTs)

For this purpose, the researchers searched the online databases to identify randomized controlled trials that assessed the impact of quercetin on BP until May 2022. Data were analyzed using a random-effects model. Subgroup analysis was performed to explore the effects in (pre)hypertensive and normotensive adults. The analysis included ten trials (841 participants in total).

The results showed that quercetin supplementation significantly decreased SBP in the mixed population (MD: -2.38mmHg) and in the normotensive subgroup (MD: -1.82mmHg) and DBP in the (pre)hypertensive subgroup (MD: -3.14mmHg).

"Findings from a meta-analysis suggest that quercetin lowers systolic blood pressure in normotensives and diastolic blood pressure in pre)hypertensive, so has a potential role in this," the researchers wrote. "However, still there is a need for more studies on this topic, particularly in hypertensive patients and regarding long-term administration effects."

Reference:

The study titled, "The effects of quercetin supplementation on blood pressure – meta-analysis," was published in Current Problems in Cardiology.

DOI: https://doi.org/10.1016/j.cpcardiol.2022.101350

Current Problems in Cardiologyquercetinhypertension

Source : Current Problems in Cardiology

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751