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  • Articaine - a safe and...

Articaine - a safe and efficacious local anaesthetic for all routine dental procedures: Study

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-09-08T23:19:47+05:30  |  Updated On 8 Sept 2021 11:19 PM IST
Articaine - a safe and efficacious local anaesthetic for all routine dental procedures: Study
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Articaine is a safe and efficacious local anaesthetic for all routine dental procedures, suggests a study published in BDJ Open.

A group of researchers from Australia conducted a study to comprehensively review the existing studies of articaine in dentistry and conduct a systematic review and meta-analysis to answer the following Population, Intervention, Comparison and Outcome question: "Is articaine a safe and efficacious local anaesthetic for routine dental treatment compared to lidocaine?"

The authors searched Medline Ovid, Medline Pubmed, Scopus, Emcare, Proquest and the Cochrane Central Register of Controlled Trials. Inclusion criteria were all existing English, human, randomised controlled trials of interventions involving 4% articaine and 2% lidocaine in routine dental treatment. Twelve studies were included for meta-analysis using Cochrane Review Manager 5 software. Anaesthetic success odds ratios were calculated using a random-effects model.

The results of the study are as follows:

· Articaine had a higher likelihood of achieving anaesthetic success than lidocaine overall and in all subgroup analyses with varying degrees of significance.

· Overall articaine had 2.17 times the likelihood of anaesthetic success of lidocaine.

· For mandibular blocks articaine had 1.5 times the likelihood of anaesthetic success of lidocaine.

· For all infiltrations, maxillary and mandibular articaine had 2.78 times the likelihood of anaesthetic success of lidocaine.

· None of the studies reported any major local anaesthetic-related adverse effects as a result of the interventions.

Thus, the researchers concluded that Articaine is a safe and efficacious local anaesthetic for all routine dental procedures in patients of all ages, and more likely to achieve successful anaesthesia than lidocaine in routine dental treatment. Neither anaesthetic has a higher association with anaesthetic-related adverse effects.

Reference:

Articaine in dentistry: an overview of the evidence and meta-analysis of the latest randomised controlled trials on articaine safety and efficacy compared to lidocaine for routine dental treatment by Martin E et. al published in the BDJ Open.

https://doi.org/10.1038/s41405-021-00082-5



Articainebdj opendental procedureslocal anaesthesia
Source : BDJ Open
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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