- Medical news & Guidelines
- Cardiology and CTVS
- Critical Care
- Diabetes and Endocrinology
- Laboratory Medicine
- Health news
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Dadra and Nagar Haveli
- Daman and Diu
- Himachal Pradesh
- Jammu & Kashmir
- Madhya Pradesh
- Tamil Nadu
- Uttar Pradesh
- West Bengal
- Medical Education
Fluoride and silver nanoparticles prevent enamel demineralization and caries: Study
According to recent research, dentists have noted that fluoride and silver nanoparticles had a significant effect on the prevention of in vitro demineralization of sound enamel and enamel caries-like lesions of varying severities.This study is published in the Journal of Dentistry. An array of chemotherapeutic agents have been examined as a strategy to prevent and arrest dental caries...
According to recent research, dentists have noted that fluoride and silver nanoparticles had a significant effect on the prevention of in vitro demineralization of sound enamel and enamel caries-like lesions of varying severities.
This study is published in the Journal of Dentistry.
An array of chemotherapeutic agents have been examined as a strategy to prevent and arrest dental caries such as the use of metal ions, antimicrobials and a variety of fluoride compounds out of which Silver diamine fluoride and nano silver fluoride compounds (NSF) possess the capability of preventing the incidence of new caries lesions and arresting the existing ones.
Furthermore, contemporary reviews as well as clinical studies did indicate that fluoride concentrations in the oral environment may have an influence on the progression and remission of dental caries.
Therefore, Bader A.Aldhaian and colleagues from the Indiana University School of Dentistry, Department of Prosthodontics, Indianapolis, USA conducted this study to investigate the effect of fluoride and silver nanoparticles on the prevention of cariogenic demineralization of sound enamel and enamel caries-like lesions of varying severities. They also aimed to determine if fluoride and silver exhibit additive or synergistic effects in preventing demineralization.
aries-like lesions of different severities (1/6/15 days) were created in bovine enamel specimens. One group remained sound. All specimens were demineralized again using a partially saturated acetic acid solution. Mimicking the intra-oral retention of fluoride and silver in vitro, this solution was supplemented with fluoride (0/1/10 ppm) and/or silver nanoparticles (0/10 ppm) in a factorial design. Changes in lesion depth (ΔL) and integrated mineral loss (ΔΔZ) were evaluated by digital transverse microradiography. Data was then analyzed.
The findings observed were-
a. Lesion severity significantly affected ΔΔZ and ΔL, after no treatment and after the treatment of fluoride and silver independently (p = 0.012 and p = 0.037, respectively).
b. Fluoride and the fluoride × lesion severity interaction were shown to be significant (p < 0.001) on ΔΔZ and ΔL.
c. Silver nanoparticles significantly affected ΔΔZ (p = 0.041), but not ΔL (p = 0.15).
d. The silver nanoparticles × lesion severity interaction was significant for ΔΔZ and ΔL (p = 0.032 and p = 0.024, respectively).
e. No interaction was observed for ΔΔZ and ΔL between fluoride and silver (p = 0.962 and p = 0.971, respectively) as well as lesion severity and the use of fluoride and silver combined (p = 0.722 and p = 0.158, respectively).
Therefore, the authors concluded that "fluoride and silver nanoparticles had a significant effect on the prevention of in vitro demineralization of sound enamel and enamel caries-like lesions of varying severities."
BDS, MDS( Pedodontics and Preventive Dentistry)
Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at email@example.com. Contact no. 011-43720751