Periodontitis tied to six-fold increase in the risk of premature birth; BMC
In a recent development, researchers have highlighted that that periodontitis is strongly associated with premature birth. The research team further recommended that Preventive solutions including the use of a periodontitis screening tool for nurses and midwives during antenatal care consultations, are highly recommended. The findings have been published in BMC Pregnancy and Childbirth .
Premature delivery is among the leading causes of perinatal mortality and morbidity in developed societies, which is an important obstetrics problem. Maternal periodontitis is a prevalent condition that has been suspected to be associated with adverse pregnancy outcomes such as premature birth. However, there are still conflicting results about this possible relationship, therefore this study was designed to test the association between maternal periodontitis and premature birth. This study also provides information about a new screening tool recommended for use by nurses and midwives to screen for periodontal diseases during antenatal consultations in order to improve the health of mothers and children.
Regarding the current study design,a retrospective case-control study was conducted at 12 health facilities in the Southern Province of Rwanda from February to August, 2018. A total of 555 women in the postpartum period were enrolled in the study. Cases and controls were enrolled in a ratio of 1:2; each enrolled case of preterm birth was followed by 2 unmatched control subjects that were next on the register and who delivered at term gestation.
A total of 185 cases of preterm deliveries and 370 controls of term delivery were enrolled in the study. Multivariate regression analysis was used and the independent variables were hierarchically entered in three groups: The first group involved demographic variables that were put in the regression model as Step 1. The second group was made up of other potential risk factors that were placed in the regression model as the second step. Periodontitis was entered in the final regression step, as it was hypothesized as the main predictor variable.
Data analysis revealed that a statistically significant association was found between periodontitis and premature birth. Women who had periodontitis had 6 times the odds of giving birth to premature birth infants compared to women who had no periodontitis (OR: 6.360, 95% CI 3.9, 10.4).
Observing the results, the team opined that "Maternal weight has also been reported to be associated with premature birth, whereby in our study the logistic regression revealed that mothers with low weight had higher chances of premature deliveries as opposed to mother with normal weight whereas the odds of having a premature birth baby was 3.2 times for underweight compared to those with normal weight mothers."
For the full article follow the link: https://doi.org/10.1186/s12884-021-03700-0
Primary source: BMC Pregnancy and Childbirth