Calcium hydroxylapatite helps improve chest wrinkles in women: Study

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-05-04T11:30:10+05:30 | Updated On 4 May 2021 3:53 PM IST

USA: Hyperdilute calcium hydroxylapatite (CaHA) significantly improves the appearance of chest wrinkles that persists for at least 1 year, finds a recent study in the Journal of Drugs in Dermatology.

CaHA is used for the treatment of moderate-to-severe facial wrinkles and folds. Its beneficial effects are due to its ability to produce immediate augmentation of soft tissue and a prolonged neocollagenesis with long-term deposition of new collagen.

Hyperdilute CaHA is being used increasingly for stimulating neocollagenesis for improving skin firmness and quality. The study by Sabrina G. Fabi from San Diego, CA, and colleagues aimed to assess the long-term effects of hyperdilute CaHA for improving chest wrinkle appearance.

The study included 20 adult females patients treated with a 1:2 dilution of CaHA. They were evaluated at week 6, week 12, day 180, and day 360 using validated Merz Décolletage Scales. A Subject Satisfaction Questionnaire was used for the assessment of overall satisfaction on a scale from 0 (Completely Dissatisfied) to 6 (Completely Satisfied).

Also Read: Eating mangoes may reduce facial wrinkles in postmenopausal women: Study

Key findings of the study include:

· Subjects achieved significant improvements in baseline Merz Décolletage Scale–Dynamic scores at week 6, after a single treatment, at week 12 (two treatments), day 180, and day 360.

· Subjects also demonstrated significant improvement in baseline Merz Décolletage Scale–At Rest scores at week 6, remaining significant at week 12, day 180, and day 360.

· Subject Satisfaction scores increased from 3.25 at day 180 to 3.59 at day 360 using a 7-point scale.

"Hyperdilute CaHA significantly improves the dynamic and resting appearance of wrinkles of the décolleté. These durable improvements persist for at least 1 year," wrote the authors.

Reference:

The study titled, "Prospective Clinical Trial Evaluating the Long-Term Safety and Efficacy of Calcium Hydroxylapatite for Chest Rejuvenation," is published in the Journal of Drugs in Dermatology.

DOI: https://jddonline.com/articles/dermatology/S1545961621P0534X

Journal of Drugs in Dermatologycalcium hydroxylapatitedermal fillerschest wrinkle

Source : Journal of Drugs in Dermatology

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751