Medical Dialogues
  • Dermatology
Login Register
This site is intended for healthcare professionals only
Login Register
  • MD Brand Connect
  • Vaccine Hub
  • MDTV
    • Breaking News
    • Medical News Today
    • Health News Today
    • Latest
    • Journal Club
    • Medico Legal Update
    • Latest Webinars
    • MD Shorts
    • Health Dialogues
  • Fact Check
  • Health Dialogues
Medical Dialogues
  • Medical News & Guidelines
      • Anesthesiology
      • Cardiology and CTVS
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endocrinology
      • ENT
      • Gastroenterology
      • Medicine
      • Nephrology
      • Neurology
      • Obstretics-Gynaecology
      • Oncology
      • Ophthalmology
      • Orthopaedics
      • Pediatrics-Neonatology
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
      • Laboratory Medicine
      • Diet
      • Nursing
      • Paramedical
      • Physiotherapy
  • Health news
      • Doctor News
      • Government Policies
      • Hospital & Diagnostics
      • International Health News
      • Medical Organization News
      • Medico Legal News
      • NBE News
      • NMC News
  • Fact Check
      • Bone Health Fact Check
      • Brain Health Fact Check
      • Cancer Related Fact Check
      • Child Care Fact Check
      • Dental and oral health fact check
      • Diabetes and metabolic health fact check
      • Diet and Nutrition Fact Check
      • Eye and ENT Care Fact Check
      • Fitness fact check
      • Gut health fact check
      • Heart health fact check
      • Kidney health fact check
      • Medical education fact check
      • Men's health fact check
      • Respiratory fact check
      • Skin and hair care fact check
      • Vaccine and Immunization fact check
      • Women's health fact check
  • AYUSH
    • Ayurveda
    • Homeopathy
    • Siddha
    • Unani
    • Yoga
  • State News
      • Andaman and Nicobar Islands
      • Andhra Pradesh
      • Arunachal Pradesh
      • Assam
      • Bihar
      • Chandigarh
      • Chattisgarh
      • Dadra and Nagar Haveli
      • Daman and Diu
      • Delhi
      • Goa
      • Gujarat
      • Haryana
      • Himachal Pradesh
      • Jammu & Kashmir
      • Jharkhand
      • Karnataka
      • Kerala
      • Ladakh
      • Lakshadweep
      • Madhya Pradesh
      • Maharashtra
      • Manipur
      • Meghalaya
      • Mizoram
      • Nagaland
      • Odisha
      • Puducherry
      • Punjab
      • Rajasthan
      • Sikkim
      • Tamil Nadu
      • Telangana
      • Tripura
      • Uttar Pradesh
      • Uttrakhand
      • West Bengal
  • Medical Education
      • Ayush Education News
      • Dentistry Education News
      • Medical Admission News
      • Medical Colleges News
      • Medical Courses News
      • Medical Universities News
      • Nursing education News
      • Paramedical Education News
      • Study Abroad
  • Industry
      • Health Investment News
      • Health Startup News
      • Medical Devices News
      • Pharma News
      • Pharmacy Education News
      • Industry Perspective
  • MDTV
      • Health Dialogues MDTV
      • Health News today MDTV
      • Latest Videos MDTV
      • Latest Webinars MDTV
      • MD shorts MDTV
      • Medical News Today MDTV
      • Medico Legal Update MDTV
      • Top Videos MDTV
      • Health Perspectives MDTV
      • Journal Club MDTV
      • Medical Dialogues Show
This site is intended for healthcare professionals only
LoginRegister
Medical Dialogues
LoginRegister
  • Home
  • Medical news & Guidelines
    • Anesthesiology
    • Cardiology and CTVS
    • Critical Care
    • Dentistry
    • Dermatology
    • Diabetes and Endocrinology
    • ENT
    • Gastroenterology
    • Medicine
    • Nephrology
    • Neurology
    • Obstretics-Gynaecology
    • Oncology
    • Ophthalmology
    • Orthopaedics
    • Pediatrics-Neonatology
    • Psychiatry
    • Pulmonology
    • Radiology
    • Surgery
    • Urology
    • Laboratory Medicine
    • Diet
    • Nursing
    • Paramedical
    • Physiotherapy
  • Health news
    • Doctor News
    • Government Policies
    • Hospital & Diagnostics
    • International Health News
    • Medical Organization News
    • Medico Legal News
    • NBE News
    • NMC News
  • Fact Check
    • Bone Health Fact Check
    • Brain Health Fact Check
    • Cancer Related Fact Check
    • Child Care Fact Check
    • Dental and oral health fact check
    • Diabetes and metabolic health fact check
    • Diet and Nutrition Fact Check
    • Eye and ENT Care Fact Check
    • Fitness fact check
    • Gut health fact check
    • Heart health fact check
    • Kidney health fact check
    • Medical education fact check
    • Men's health fact check
    • Respiratory fact check
    • Skin and hair care fact check
    • Vaccine and Immunization fact check
    • Women's health fact check
  • AYUSH
    • Ayurveda
      • Ayurveda Giuidelines
      • Ayurveda News
    • Homeopathy
      • Homeopathy Guidelines
      • Homeopathy News
    • Siddha
      • Siddha Guidelines
      • Siddha News
    • Unani
      • Unani Guidelines
      • Unani News
    • Yoga
      • Yoga Guidelines
      • Yoga News
  • State News
    • Andaman and Nicobar Islands
    • Andhra Pradesh
    • Arunachal Pradesh
    • Assam
    • Bihar
    • Chandigarh
    • Chattisgarh
    • Dadra and Nagar Haveli
    • Daman and Diu
    • Delhi
    • Goa
    • Gujarat
    • Haryana
    • Himachal Pradesh
    • Jammu & Kashmir
    • Jharkhand
    • Karnataka
    • Kerala
    • Ladakh
    • Lakshadweep
    • Madhya Pradesh
    • Maharashtra
    • Manipur
    • Meghalaya
    • Mizoram
    • Nagaland
    • Odisha
    • Puducherry
    • Punjab
    • Rajasthan
    • Sikkim
    • Tamil Nadu
    • Telangana
    • Tripura
    • Uttar Pradesh
    • Uttrakhand
    • West Bengal
  • Medical Education
    • Ayush Education News
    • Dentistry Education News
    • Medical Admission News
    • Medical Colleges News
    • Medical Courses News
    • Medical Universities News
    • Nursing education News
    • Paramedical Education News
    • Study Abroad
  • Industry
    • Health Investment News
    • Health Startup News
    • Medical Devices News
    • Pharma News
      • CDSCO (Central Drugs Standard Control Organisation) News
    • Pharmacy Education News
    • Industry Perspective
  • Home
  • Dermatology
  • Dermatology News
  • Increased prevalence...

Increased prevalence of depression and anxiety observed in hidradenitis suppurativa patients: JAMA

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2025-08-04T22:00:40+05:30  |  Updated On 4 Aug 2025 10:01 PM IST
mental illness after childbirth
  • facebook
  • twitter
  • linkedin
  • whatsapp
  • Telegram
  • Email

A new study published in the Journal of American Medical Association showed that new-onset anxiety and sadness were more likely to occur in hidradenitis suppurativa (HS) patients.

Although there is a higher chance of developing anxiety and depression in patients with HS, it is unclear if the severity of the illness is a possible risk factor in and of itself. Thus, this study evaluated the risk of both new-onset and recurring anxiety and depression in HS patients, as well as its correlation with the severity of the condition when compared to the general population.

Danish HS patients who were age and sex matched 1:4 with the individuals without HS from the Danish national registries were included in this population-based cohort research, which ran from 1997 to 2022. Analysis of the data took place between July 18, 2024, and May 20, 2025. First diagnoses of anxiety or depression, as well as the first diagnoses of both as distinct outcomes after the index date, were the primary outcomes.

Using Cox regression models that controlled for socioeconomic and demographic characteristics as well as comorbidities, incidence rates (IRs) and hazard ratios (HRs) were computed for the first episode of anxiety or depression after baseline. Treatments (systemic nonbiologics, topicals, or biologics) and hospitalizations for HS-related surgical operations (0, 1, 2, or ≥3) were used to determine the severity of the disease.

There were 40,125 controls and 10,206 HS patients in total. Of those who got HS-related therapies throughout the research period, 12.0% received just topical, 55.5% received systemic nonbiologic, 6.5% received biologic, and 25.9% did not get any. The adjusted HRs for new-onset anxiety and depression were 1.48 (95% CI, 1.38-1.56; P <.001) and 1.69 (95% CI, 1.57-1.81; P <.001), respectively.

When therapy was stratified, the HRs for anxiety or depression were 1.38 (95% CI, 1.01-1.87; P <.05) for biologics, 1.62 (95% CI, 1.41-1.85; P <.001) for topicals, and 1.61 (95% CI, 1.51-1.72; P <.001) for systemic non-biologics. The HRs were 1.44 (95% CI, 1.36-1.53; P <.001), 1.66 (95% CI, 1.53-2.17), 1.59 (95% CI, 1.33-1.90; P <.001), and 1.60 (95% CI, 1.40-1.85; P <.001) by 0, 1, 2, or 3 hospitalizations for HS-related surgical operations, respectively.

When compared to controls, HS patients had higher rates of anxiety (5.9% vs 0.5%; P <.001) and depression (7.0% vs 0.3%; P <.001), but there was no difference in the risk of recurring anxiety (HR, 1.22 [95% CI, 0.89-1.66]; P =.22) or depression. Overall, clinicians should be aware of mental disease at all severity levels and treat patients in a multidisciplinary environment, since this research highlights that anxiety and depression can manifest independently of the severity of the disease.

Source:

Holgersen, N., Rosenø, N. A. L., Nielsen, V. W., Hjorthøj, C., Nordentoft, M., Garg, A., Strunk, A., Thyssen, J. P., Nilsson, S. F., Egeberg, A., & Thomsen, S. F. (2025). Risk of new-onset and recurrent depression and anxiety among patients with hidradenitis suppurativa. JAMA Dermatology (Chicago, Ill.). https://doi.org/10.1001/jamadermatol.2025.2298

JAMA Dermatologyhidradenitis suppurativadepression
Source : JAMA Dermatology
Jacinthlyn Sylvia
Jacinthlyn Sylvia

    Neuroscience Masters graduate

    Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

    Show Full Article
    Next Story

    Editorial

    Penicillin-Binding Protein 3 Inserts in E.coli:A Growing Burden of Underreported Threat

    Penicillin-Binding Protein 3 Inserts in E.coli:A Growing Burden of Underreported Threat

    Management of Hypertension: How Innovative Packaging Can Improve Patient Outcomes?

    Management of Hypertension: How Innovative Packaging Can Improve Patient Outcomes?

    Uncontrolled T2D in India: Valuable Consideration for Dapagliflozin Sitagliptin Combination

    Uncontrolled T2D in India: Valuable Consideration for Dapagliflozin Sitagliptin Combination

    JAPI Releases Dedicated Supplement Addressing Clinical Needs for Adult Vaccination in India

    JAPI Releases Dedicated Supplement Addressing Clinical Needs for Adult Vaccination in India

    Cuticapil Stem Hair Serum as Add-On to Minoxidil Shows Superior Hair Growth in Androgenetic Alopecia : Indian Real World Data

    Cuticapil Stem Hair Serum as Add-On to Minoxidil Shows Superior Hair Growth in Androgenetic Alopecia...

    View All

    Journal Club Today

    Shedding Weight, Losing Muscle: Study Links GLP-1 Drugs to Reduced Muscle Mass

    Shedding Weight, Losing Muscle: Study Links GLP-1 Drugs to Reduced Muscle Mass

    View All

    Health News Today

    Health Bulletin 04/August/ 2025

    Health Bulletin 04/August/ 2025

    View All
    © 2022 All Rights Reserved.
    Powered By: Hocalwire
    X
    We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok