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  • Topical Cidofovir...

Topical Cidofovir Therapy Effective in Clearing Cutaneous Warts

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 19 Jan 2024 8:00 PM  |  Updated On 19 Jan 2024 8:00 PM
Topical Cidofovir Therapy Effective in Clearing Cutaneous Warts
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Cutaneous warts are frequently difficult to treat successfully, with high rates of recurrence and infrequent complete removal. The human papillomavirus (HPV), which causes warts, is one of many DNA viruses that topical cidofovir, an antiviral drug, has been shown to be effective against in a recent study. The outcomes were published in Journal of Drugs in Dermatology.

The purpose of the study was to evaluate safety and effectiveness of cidofovir in the treatment of non-genital warts. The existing literature was thoroughly reviewed by the researchers, who searched the PubMed and Google Scholar databases for pertinent case studies and reports.

The comprehensive analysis included 13 case reports, five case series, six retrospective chart reviews, and one clinical study, comprising a total of 603 patients. Among these patients, 212 were treated with topical cidofovir, which led to the clearance of warts in an impressive 55.2% of cases. Even more encouraging, no recurrence of lesions was reported in the two months to three years following treatment, with a mean follow-up of 15.8 months.

While the study shows substantial promise for cidofovir, some patients did report mild local side effects, including erythema, pruritus, and burning. Nevertheless, these side effects appeared to be manageable and did not outweigh the benefits of wart clearance.

This breakthrough is particularly significant as treatment options for stubborn non-genital warts are often limited, with varying degrees of efficacy. The findings suggest that topical cidofovir may provide an effective, safe, and cost-friendly alternative for those dealing with persistent non-genital warts.

Despite the promising results, the researchers underscored the importance of conducting controlled clinical trials to validate these findings. This additional research would not only confirm the efficacy and safety of cidofovir but also contribute to the ongoing efforts to improve treatment options for non-genital warts.

In the ongoing battle against these pesky skin conditions, topical cidofovir could be a game-changer. Further investigation will be necessary, but this study offers hope for those who have struggled with the recurrence of non-genital warts.

Source:

Cook, M. K., Hagen, E. M., & Feldman, S. R. (2023). Cidofovir in the management of non-genital warts: A review. Journal of Drugs in Dermatology: JDD, 22(10), 1009–1016. https://doi.org/10.36849/jdd.7258

Journal of Drugs in DermatologyCutaneous WartsCidofovir
Source : Journal of Drugs in Dermatology
Jacinthlyn Sylvia
Jacinthlyn Sylvia

    Neuroscience Masters graduate

    Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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