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Dietary Vitamin D Linked to Better Cognitive Function and Mood in Elderly: Study

Dr. Shravani DaliWritten by Dr. Shravani Dali Published On 2025-05-10T08:30:31+05:30  |  Updated On 10 May 2025 8:30 AM IST
Dietary Vitamin D Linked to Better Cognitive Function and Mood in Elderly: Study
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Research indicates that higher dietary intake of vitamin D is associated with improved cognitive performance and reduced depressive symptoms in older adults. While these findings are promising, further longitudinal studies are necessary to confirm a causal relationship and understand the biological mechanisms involved.

Vitamin D is known to have a potential impact on cognitive function and mental health. This study aims to assess the association between dietary vitamin D intake and cognitive performance, as well as depression, in an elderly U.S. population. Data from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 were analyzed. A total of 1,344 elderly participants were categorized into three tertiles based on their dietary vitamin D intake (D2 + D3). Cognitive function was measured using the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) test, Digit Symbol Substitution Test (DSST), and Animal Fluency Test, while depression was assessed through the Patient Health Questionnaire-9 (PHQ-9). Adjustments were made for confounding variables, including age, sex, race, education, physical activity level, and other dietary factors. Results: After adjustment for confounders, individuals in the 3rd tertile of vitamin D intake (≥4.9 mcg/day) had significantly reduced odds of low performance on the CERAD test (OR: 0.77, 95% CI: 0.57-0.98; p = 0.031) and Animal Fluency test (OR: 0.63, 95% CI: 0.49-0.85; p = 0.013) compared to the 1st tertile of intake (≤2.4 mcg/day). Similarly, participants in the 3rd tertile of vitamin D intake had lower odds of depression (PHQ-9 score > 4) after adjustment (OR: 0.68, 95% CI: 0.48-0.99; p = 0.046). The findings suggest that dietary vitamin D intake is associated with improved cognitive function and depressive symptoms in elderly individuals. However, further longitudinal studies are needed to establish causality and explore the underlying mechanisms.

Reference:

Chen H, Pang X, Huang Y. Higher dietary vitamin D intake influences brain and mental function in elderly Americans: a cross-sectional analysis. Front Nutr. 2025 Apr 9;12:1564568. doi: 10.3389/fnut.2025.1564568. PMID: 40271436; PMCID: PMC12016215.


Keywords

Dietary, Vitamin D, Linked, Better, Cognitive, Function, Mood, Elderly, Chen H, Pang X, Huang Y, NHANES; cognitive function; depression; elderly; vitamin D.





DietaryVitamin DLinkedBetterCognitiveFunctionMoodElderly
Source : Frontiers in nutrition
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

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