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  • High dietary acid load...

High dietary acid load can potentially worsen cardiometabolic risk factors, study reveals

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 23 May 2024 2:30 PM  |  Updated On 24 May 2024 6:55 AM
High dietary acid load can potentially worsen cardiometabolic risk factors, study reveals
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Iran: A recent meta-analysis revealed that high dietary acid load (DAL) can be considered an independent risk factor for increasing anthropometric indices, triglyceride (TG), and blood pressure. The findings were published online in Nutrition, Metabolism and Cardiovascular Diseases.

The dietary acid load is determined by the balance of acid-inducing foods, such as eggs, meats, cheese and cereal grains, and base-inducing foods, such as vegetables and fruits.

Previous studies have revealed an association between chronic metabolic acidosis and cardiometabolic risk factors. Mohammad Alizadeh, Tabriz University of Medical Sciences, Tabriz, Iran, and colleagues aimed to explore the association between Potential Renal Acid Load (PRAL) and Net Endogenous Acid Production (NEAP) with these risk factors in an updated meta-analysis.

For this purpose, the researchers searched the online databases up to May 2023. The mean of body mass index (BMI), waist circumference (WC), high- and low-density lipoprotein-cholesterol (HDL-C and LDL-C), triglyceride, fasting blood sugar (FBS), total cholesterol (TC), and systolic- and diastolic blood pressure (SBP and DBP) in highest category versus lowest categories of NEAP and PRAL were recorded. Effect sizes were generated as weighted mean difference (WMD).

The researchers reported the following findings:

  • Low PRAL and NEAP scores are significantly related to lower systolic BP and diastolic BP.
  • Lower PRAL and NEAP scores are significantly associated with lower waist circumference values.
  • The lowest versus highest categories of PRAL were associated with lower body mass index.
  • There was a significant association between low serum triglyceride and low PRAL score.

"Findings showed that SBP, DBP, and WC had a significant difference in the upper and lower categories of PRAL (WMDSBP: -1.466 mmHg, WMDDBP: -0.710 mmHg, and WMDWC: -0.819 cm) or NEAP (WMDSBP: -1.690 mmHg, WMDDBP: -1.076 mmHg, and WMDWC: -1.325 cm)," the researchers reported.

"The lowest versus highest categories of dietary PRAL were associated with lower BMI (WMDPRAL: -0.297 kg/m2) and TG (WMD: -2.280 mg/dl)."

"High dietary acid load can be considered as an independent risk factor for increasing blood pressure, anthropometric indices, and TG," they concluded.

Reference:

Dolati, S., Razmjouei, S., Faghfouri, A. H., Moridpour, A. H., & Alizadeh, M. (2024). A high dietary acid load can potentially exacerbate cardiometabolic risk factors: An updated systematic review and meta-analysis of observational studies. Nutrition, Metabolism and Cardiovascular Diseases. https://doi.org/10.1016/j.numecd.2024.01.013


Nutrition Metabolism and Cardiovascular Diseasescardiometabolic risk factorsdietary acid loadchronic metabolic acidosis
Source : Nutrition, Metabolism and Cardiovascular Diseases
Medha Baranwal
Medha Baranwal

    MSc. Biotechnology

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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