Higher intakes of dairy foods tied to higher risk of prostate cancer

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-06-16T20:45:00+05:30 | Updated On 16 Jun 2022 8:45 PM IST

Higher intakes of dairy foods tied to higher risk of prostate cancer, finds a new study. Further substances other than calcium play a role in the risk dairy foods pose for prostate cancer.

The study has been published in The American Journal of Clinical Nutrition

Prostate cancer is the most common noncutaneous cancer in American males. Causal links between dairy, or dietary calcium, and this cancer are considered suggestive but limited.

A study was conducted to evaluate these associations in a large North American cohort, including many with no (or very low) dairy intake and much calcium from nondairy sources.

A prospective cohort study of 28,737 Seventh-day Adventist men in the United States and Canada, of whom 6389 were of black ethnicity. Diet was measured by FFQ, and 275 male participants also provided repeated 24-h dietary recalls as a calibration substudy. Incident cancers were mainly found by matching with cancer registries. Analyses used multivariable proportional hazards regressions and regression calibration for some analyses.

Results

In total, 1254 (190 advanced) incident prostate cancer cases were found during an average 7.8 y of follow-up. Men at the 90th percentile of dairy intake (430 g/d) compared with the 10th percentile (20.2 g/d) had higher prostate cancer risk
Similar findings, comparing the same g/d intakes, were demonstrated for advanced prostate cancers for nonadvanced cases in black participants and when excluding vegan participants
Calibrated dairy (g/d) regressions (all participants and all prostate cancers), adjusting for dietary measurement error, found a HR of 1.75
Comparing 90th percentile intake to zero intakes (uncalibrated), the HR was 1.62.
There was no evidence of an effect of higher (905 mg/d) compared with lower (349 mg/d) intakes of nondairy calcium

Men with higher intake of dairy foods, but not nondairy calcium, had a higher risk of prostate cancer compared with men having lower intakes. Associations were nonlinear, suggesting greatest increases in risk at relatively low doses.

Reference:

Dairy foods, calcium intakes, and risk of incident prostate cancer in Adventist Health Study–2 Get by Michael J Orlich, et al. published in The American Journal of Clinical Nutrition

https://doi.org/10.1093/ajcn/nqac093

dairy intakecalcium intakeprostate cancerSeventh-day Adventistsvegetariansvegansregression calibrationcohort studyAfrican AmericanThe American Journal of Clinical Nutrition

Source : The American Journal of Clinical Nutrition

Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751