- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Increased vitamin D levels improve pregnancy outcomes in IVF: Study
Italy: Increased serum and follicular fluid (FF) levels of vitamin D in women aged 36 yrs undergoing IVF is associated with favorable pregnancy rate, finds a recent study in the journal European Review for Medical and Pharmacological Sciences.
Vitamin D is a secosteroid hormone having both immunomodulatory and antiproliferative effects. It is also involved in placental steroidogenesis and endometrial decidualization suggesting their role in other gynecological functions, including assisted reproductive technology (ART). However reported data on its implication in pregnancy outcomes during In Vitro Fertilization (IVF) programs has been controversial. In order to elucidate the role of vitamin D in ART success, D. Baldini, Momò Fertilife Clinic, Bisceglie, Italy, and colleagues aimed to evaluate serum and FF vitamin D levels in infertile women concerning the pregnancy rate.
For this purpose, the researchers evaluated 446 patients, under the age of 42 years old in the period between January 2018 and December 2019. In order to respect the exclusion criteria, only 103 of them were enrolled for the study concerning the VitD evaluation in serum and follicular fluid at the time of the egg retrieval. The patients were divided in 34 pregnant patients (Group 1) and 69 non-pregnant ones (Group 2). Furthermore, the collection of these data gave the opportunity to assess a possible correlation between the VitD levels and the achievement of pregnancy in the performed IVF cycles.
Key findings of the study include:
- The main differences were observed concerning follicle numbers of 17-21 mm, the number of retrieved oocytes, as well as the number of mature oocytes among the different groups.
- Different reference ranges, established according to the pregnancy outcomes, revealed that pregnant women with >36 yrs showed significantly higher levels of VitD.
"Our results showed that increased serum and FF-VitD levels in women undergoing IVF with age ≥36 yrs, were significantly associated with a favorable outcome to achieve and carry on with the pregnancy," concluded the authors.
Reference:
The study titled, "Increased bioavailability of Vitamin D improved pregnancy outcomes in in vitro fertilization cycles, only in patients over 36 years: a cross-sectional study," is published in the journal European Review for Medical and Pharmacological Sciences.
DOI: https://www.europeanreview.org/article/26453
MSc. Biotechnology
Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at  editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751