Very low-carb ketogenic diet not tied to increased LDL cholestrol in diabetes

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-03-15T09:30:30+05:30 | Updated On 15 March 2022 9:30 AM IST

China: Low-carbohydrate ketogenic (VLCK) diet treatment to lower blood sugar in patients with type 2 diabetes mellitus (T2DM) is not associated with increased levels of total cholesterol and LDL, and decreased HDL levels, reveals recent study. Further, the diet is shown to achieve a short-term reduction of triglyceride levels. The study appears in the journal Nutricion Hospitalaria.

Meijuan Li and Jingyun Yuan from Zhejiang University conducted the study with an objective to evaluate the lipid metabolism of patients with T2DM after VLCK diet treatment, with an order to provide an evidence-based basis for better dietary management and comprehensive treatment of diabetes patients.

For this purpose, the researchers searched the online databases for randomized controlled trial about VLCK diet on lipid metabolism of T2DM up to September 2021. Data analysis was done using the Stata 15.0; standardized mean difference (SMD) was used as effect size. A total of ten articles were included in this meta-analysis.

Based on the study, the researchers revealed the following:

There were no significant differences between the two groups in total cholesterol (SMD = -0.07), HDL (SMD = 0.13) and LDL (SMD = 0.07) levels after treatment.
No difference was found in total cholesterol, HDL, and LDL levels between the two groups after 3, 6, and 12 months of treatment.
Triglyceride levels decreased after VLCK diet compared with control (SMD = -0.49).
A marked reduction of triglyceride levels was identified after 3 months of VLCK diet treatment (SMD = -0.69), without significant difference after 6 and 12 months.

To conclude, patients with type 2 diabetes who receive a VLCK diet are not associated with increased levels of total cholesterol and LDL, and decreased levels of HDL. The researchers wrote that, "additionally, this diet can achieve a short-term reduction of triglyceride levels."

Reference:

Li M, Yuan J. Effects of very low-carbohydrate ketogenic diet on lipid metabolism in patients with type II diabetes mellitus: a meta-analysis. Nutr Hosp. 2022 Mar 4. English. doi: 10.20960/nh.03987. Epub ahead of print. PMID: 35243868.

KEYWORDS: type 2 diabetes, very low-carbohydrate ketogenic diet, diet, low carb, cholesterol, LDL, HDL, triglyceride, lipids, metabolism, Nutricion Hospitalaria, ketogenic, blood sugar, Meijuan Li, Jingyun Yuan

type 2 diabetesvery low-carbohydrate ketogenic dietdietNutricion Hospitalaria

Source : Nutricion Hospitalaria

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751