- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
FLIP Panometry as effective as high-resolution manometry for detecting hiatus hernia
A new study published in Neurogastroenterology and Motility Journal suggests that, although esophageal distension with functional luminal imaging probe (FLIP) testing seems to provoke and/or expand an hiatus hernia (HH) in an extra 25% of individuals, FLIP can identify HH with a considerable agreement with high-resolution manometry (HRM).
Probe for functional luminal imaging Panometry analyzes the biomechanics and motility of the esophagus reaction to distension. In FLIP experiments, we have shown that hiatus hernia is seen as a gap between the crural diaphragm (CD) and lower esophageal sphincter (LES), similar to what is seen with high-resolution manometry. To compare FLIP findings to those from endoscopy and HRM in the identification of HH, Dustin A. Carlson and colleagues carried out this investigation.
In all, 100 participants who completed FLIP while undergoing sedated endoscopy and HRM were included in the research. On FLIP and HRM, LES-CD separation was measured, with the presence of HH being indicated by LES-CD ≥1 cm. The kappa (κ) statistic was used to assess the level of agreement.
The key findings of this study were:
1. With a high degree of agreement between the trials (84% agreement; = 0.667), hiatal hernias were seen in 32% of patients on HRM and 44% of patients on FLIP.
2. On FLIP, there were 11 individuals with an "enlarged" HH (LES-CD 2 cm bigger than on HRM) and 14 patients with a "new" HH (HH not seen on HRM).
3. Patients with new or enlarged HH on FLIP experienced delayed esophageal emptying on timed barium esophagogram (TBE) more frequently than those without: 2/12 (17%) compared to 7/11 (64%); p = 0.017.
In conclusion, this study showed that when patients are being assessed for esophageal motility problems, esophageal distension testing using FLIP Panometry may help and perhaps improve the assessment of HH. Additionally, using a supplementary examination with HRM and FLIP Panometry may make it easier to identify clinically important subgroups of HH that may have an effect on mechanical obstruction or gastroesophageal reflux disease. In the end, more research is required to fully assess the unique discoveries described in this study and to define the clinical implications.
Reference:
Carlson, D. A., Kahrilas, P. J., Simlote, A., Vespa, E., Teitelbaum, E., Hungness, E., Kou, W., & Pandolfino, J. E. (2022). Identifying hiatal hernia with impedance planimetry during esophageal distension testing. In Neurogastroenterology & Motility. Wiley. https://doi.org/10.1111/nmo.14470
Neuroscience Masters graduate
Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751