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STRETTA Improves Refractory GERD in Patients with Previous Gastric Surgery
Symptoms of gastro-oesophagal reflux disease (GERD) are common in patients who have undergone previous gastric surgery. In a study, the researchers have found that STRETTA is successful in reducing refractory GERD in patients with a history of gastric surgery. The study findings were published in the journal clinical endoscopy.
STRETTA is the only endoscopic radiofrequency device licensed for GERD in the UK. STRETTA improves the quality of life and reduces the need for anti-reflux medication in select patients, especially those with uncomplicated GERD. Studies have shown that STRETTA is effective in patients with refractory GERD with a history of previous gastric surgery. However, it has been reported only in a few studies. To further evaluate, researchers of the James Cook University Hospital, UK, conducted a study and reviewed the outcomes of STRETTA in patients with medically refractory GERD who had undergone previous gastric surgery.
In this prospective cohort study, the researchers evaluated a database in a British centre and included 11 patients with GERD and a history of previous gastric surgery. They evaluated the anti-reflux medication pre-and-post-STRETTA. They assessed the outcomes objectively by the change in anti-reflux medication and subjectively through a pre-and post-procedure GERD-health-related quality of life (HRQL) questionnaire. The median length of follow-up was 23 months.
Key findings of the study were:
- Upon evaluation, the researchers found that nine patients had improved GERD-HRQL scores following STRETTA (82%).
- Among 7 patients who underwent fundoplication, they noted that all reported improved symptoms, with 3 patients discontinuing the medication and 3 patients on a reduced dose of proton pump inhibitor.
- Of 4 patients who underwent surgery other than fundoplication, they noted 2 had improvement and discontinued the proton pump inhibitor. While the other two patients reported no improvement.
The authors concluded, " This case series demonstrates that STRETTA is successful in reducing refractory GERD in patients with a history of gastric surgery. The outcomes in this cohort of patients were comparable to published outcomes in patients with uncomplicated GERD who have not previously undergone a gastric intervention."
For further information:
https://www.e-ce.org/journal/view.php?doi=10.5946/ce.2020.243
Dr Kartikeya Kohli is an Internal Medicine Consultant at Sitaram Bhartia Hospital in Delhi with super speciality training in Nephrology. He has worked with various eminent hospitals like Indraprastha Apollo Hospital, Sir Gangaram Hospital. He holds an MBBS from Kasturba Medical College Manipal, DNB Internal Medicine, Post Graduate Diploma in Clinical Research and Business Development, Fellow DNB Nephrology, MRCP and ECFMG Certification. He has been closely associated with India Medical Association South Delhi Branch and Delhi Medical Association and has been organising continuing medical education programs on their behalf from time to time. Further he has been contributing medical articles for their newsletters as well. He is also associated with electronic media and TV for conduction and presentation of health programs. He has been associated with Medical Dialogues for last 3 years and contributing articles on regular basis.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751