Medical Bulletin 29/December/2021 - Video
Overview
Here are Top Medical stories of the day
Viagra use linked to reduced risk of Alzheimer's disease
A new Cleveland Clinic-led study has identified sildenafil - an FDA-approved therapy for erectile dysfunction (Viagra) and pulmonary hypertension (Ravatio) – as a promising drug candidate to help prevent and treat Alzheimer's disease.
According to findings published in Nature Aging, the research team, led by Feixiong Cheng, Ph.D., of Cleveland Clinic's Genomic Medicine Institute, used computational methodology to screen and validate FDA-approved drugs as potential therapies for Alzheimer's disease. Through a large-scale analysis of a database of more than 7 million patients, they determined that sildenafil is associated with 69% reduced incidence of Alzheimer's disease, indicating the need for follow-up clinical trial testing of the drug's efficacy in patients with the disease.
For more details, check out the full story on the link below:
Viagra Use Linked To Reduced Risk Of Alzheimer's Disease
Barcitinib effective in severe nail lichen planus- 1st case report
For more details, check out the full story on the link below:
Barcitinib Effective In Severe Nail Lichen Planus- 1st Case Report
Prescribing abortion pill without restrictions is safe and effective, finds a UBC-led study. One of the key findings from the study is that abortion has remained safe after Canada removed restrictions on the medical abortion pill mifepristone in November 2017.
The study has been published in the New England Journal of Medicine.
For more details, check out the full story on the link below:
Prescribing Abortion Pill Without Restrictions Safe And Effective, NEJM Study Finds
A lack of adequate folate may negatively impact healing in patients with diabetic foot ulcers, suggests a recent study published in the Journal of Human Nutrition and Dietetics. This implies that wound management of people with diabetic foot ulceration (DFU) should include a regular assessment of dietary intake in order to recognize deficiencies in macro-and micronutrients. Addressing these inadequacies may help to optimize healing.
Individuals with DFU are required to take adequate nutrition, therefore, an assessment of dietary intake is critical. A lack of proper intake of nutrients including protein, zinc, and vitamins C and D have all been related to poor wound healing. However, the comprehensive dietary intake of Australian adults with DFU is poorly understood. Peta Ellen Tehan, University of Newcastle, Callaghan, NSW, Australia, and colleagues, therefore, aimed to describe the dietary intake of adults with DFU in an Australian setting in a cross-sectional study.
For more details, check out the full story on the link below:
Inadequate Folate Intake Tissue Impairs Repair Process In Diabetic Foot Ulcer: Study
A new study found that eating ultra-processed meals raised the incidence of type 2 diabetes as a dose-response impact, with moderate to high evidence of believability. The findings of this study were published in the International Journal of Epidemiology.
Consumption of certain food categories has been linked to an increased risk of diabetes. However, there is no evidence from meta-analyses that assesses the risk of diabetes associated with the intake of ultra-processed food. Therefore, this study was conducted by Felipe Mendes Delpino and the team with the objective to conduct a systematic review of the literature on the relationship between ultra-processed food intake and the risk of type 2 diabetes, and to quantify this risk using a meta-analysis.
For more details, check out the full story on the link below:
Ultra-Processed Food Directly Linked To Risk Of Type 2 Diabetes: Study
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