Antiseizure medication linked to lower vitamin D levels
Treatment with the antiseizure medication (ASM) carbamazepine is related to a reduction in vitamin D levels, shows a recent study. The findings from the meta-analysis, published in the journal Epilepsy Research, support the use of alternative ASMs as first-line agents. Also, the researchers strongly stress considering vitamin D supplementation for patients who are prescribed carbamazepine.
There have been concerns regarding the impact of enzyme-inducing ASMs on vitamin D -- an important molecule in both inflammation and bone metabolism pathways. Though there have been studies evaluating the relationship between chronic use of carbamazepine and vitamin D levels, there is no availability of comprehensive review to inform practitioners and policymakers.
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Dr. Nandita Mohan
BDS, MDS( Pedodontics and Preventive Dentistry)