In observational studies, vitamin D has been inconsistently associated with reduced risk of several autoimmune diseases, and a large randomized, controlled trial has been lacking.
Supplementation with vitamin D and fish oil-derived omega-3 fatty acids may prevent from autoimmune diseases, suggests a large prospective randomized trial. A nationwide randomized trial by Jill Hahn and team revealed that supplementation for 5 years with vitamin D3 and or n-3 fatty acids reduced incident autoimmune disease by 25-30% in older adults than those who received neither supplement. The effect of vitamin D3 appeared to be stronger after 2 years of supplementation.
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Dr. Nandita Mohan
BDS, MDS( Pedodontics and Preventive Dentistry)