Medical Dialogues
  • Dermatology
Login Register
This site is intended for healthcare professionals only
Login Register
  • Medical Jobs
  • Medical Matrimony
  • MD Brand Connect
  • MDTV
    • Anesthesia
    • CTVS
    • Cardiology
    • Critical Care
    • Dentistry
    • Dermatology
    • Diabetes and Endocrinology
    • Diet and nutrition
    • ENT
    • Gastroenterology
    • Health Dialogues
    • Health News today
    • Health Shorts
    • Health Updates
    • Health video of the day
    • Laboratory Medicine
    • Latest Videos
    • Latest Webinars
    • MD shorts
    • Medical News Today
    • Medical Updates
    • Medical Video of the day
    • Medicine
    • Medico Legal Update
    • Nephrology
    • Neurology and Neurosurgery
    • Obstetrics and Gynaecology
    • Oncology
    • Ophthalmology
    • Orthopaedics
    • Pediatrics & Neonatology
    • Psychiatry
    • Pulmonology
    • Radiology
    • Surgery
    • Top Videos
    • Urology
Medical Dialogues
  • Medical News
      • Anesthesiology
      • Cardiology and CTVS
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endocrinology
      • ENT
      • Gastroenterology
      • Medicine
      • Nephrology
      • Neurology
      • Obstretics-Gynaecology
      • Oncology
      • Ophthalmology
      • Orthopaedics
      • Pediatrics-Neonatology
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
      • Laboratory Medicine
      • Diet
      • Nursing
      • Paramedical
      • Physiotherapy
  • Health news
      • Doctor News
      • Government Policies
      • Hospital & Diagnostics
      • International Health News
      • MCI News
      • Medical Organization News
      • Medico Legal News
      • NBE News
      • NMC News
  • Medical Guidelines
      • Anesthesiology
      • Cardiology and CTVS
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endocrinology
      • ENT
      • Gastroenterology
      • Medicine
      • Nephrology
      • Neurology
      • Obstretics-Gynaecology
      • Oncology
      • Ophthalmology
      • Orthopaedics
      • Pediatrics-Neonatology
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
      • Laboratory Medicine
      • Diet
      • Nursing
      • Paramedical
      • Physiotherapy
  • AYUSH
    • Ayurveda
    • Homeopathy
    • Siddha
    • Unani
    • Yoga
  • State News
      • Andaman and Nicobar Islands
      • Andhra Pradesh
      • Arunachal Pradesh
      • Assam
      • Bihar
      • Chandigarh
      • Chattisgarh
      • Dadra and Nagar Haveli
      • Daman and Diu
      • Delhi
      • Goa
      • Gujarat
      • Haryana
      • Himachal Pradesh
      • Jammu & Kashmir
      • Jharkhand
      • Karnataka
      • Kerala
      • Ladakh
      • Lakshadweep
      • Madhya Pradesh
      • Maharashtra
      • Manipur
      • Meghalaya
      • Mizoram
      • Nagaland
      • Odisha
      • Puducherry
      • Punjab
      • Rajasthan
      • Sikkim
      • Tamil Nadu
      • Telangana
      • Tripura
      • Uttar Pradesh
      • Uttrakhand
      • West Bengal
  • Medical Education
      • Ayush Education News
      • Dentistry Education News
      • Medical Admission News
      • Medical Colleges News
      • Medical Courses News
      • Medical Universities News
      • Nursing education News
      • Paramedical Education News
      • Study Aborad
  • Industry
    • Health Investment News
    • Health Startup News
    • Medical Devices News
    • Pharma News
    • Pharmacy Education News
  • MDTV
      • Anesthesia
      • CTVS
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endocrinology
      • Diet and nutrition
      • ENT
      • Gastroenterology
      • Health Dialogues
      • Health News today
      • Health Shorts
      • Health Updates
      • Health video of the day
      • Laboratory Medicine
      • Latest Videos
      • Latest Webinars
      • MD shorts
      • Medical News Today
      • Medical Updates
      • Medical Video of the day
      • Medicine
      • Medico Legal Update
      • Nephrology
      • Neurology and Neurosurgery
      • Obstetrics and Gynaecology
      • Oncology
      • Ophthalmology
      • Orthopaedics
      • Pediatrics & Neonatology
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Top Videos
      • Urology
This site is intended for healthcare professionals only
LoginRegister
Medical Dialogues
LoginRegister
  • Home
  • Medical news
    • Anesthesiology
    • Cardiology and CTVS
    • Critical Care
    • Dentistry
    • Dermatology
    • Diabetes and Endocrinology
    • ENT
    • Gastroenterology
    • Medicine
    • Nephrology
    • Neurology
    • Obstretics-Gynaecology
    • Oncology
    • Ophthalmology
    • Orthopaedics
    • Pediatrics-Neonatology
    • Psychiatry
    • Pulmonology
    • Radiology
    • Surgery
    • Urology
    • Laboratory Medicine
    • Diet
    • Nursing
    • Paramedical
    • Physiotherapy
  • Health news
    • Doctor News
    • Government Policies
    • Hospital & Diagnostics
    • International Health News
    • MCI News
    • Medical Organization News
    • Medico Legal News
    • NBE News
    • NMC News
  • Medical Guidelines
    • Anesthesiology
    • Cardiology and CTVS
    • Critical Care
    • Dentistry
    • Dermatology
    • Diabetes and Endocrinology
    • ENT
    • Gastroenterology
    • Medicine
    • Nephrology
    • Neurology
    • Obstretics-Gynaecology
    • Oncology
    • Ophthalmology
    • Orthopaedics
    • Pediatrics-Neonatology
    • Psychiatry
    • Pulmonology
    • Radiology
    • Surgery
    • Urology
    • Laboratory Medicine
    • Diet
    • Nursing
    • Paramedical
    • Physiotherapy
  • Medical Education
    • Ayush Education News
    • Dentistry Education News
    • Medical Admission News
    • Medical Colleges News
    • Medical Courses News
    • Medical Universities News
    • Nursing education News
    • Paramedical Education News
    • Study Aborad
  • Industry
    • Health Investment News
    • Health Startup News
    • Medical Devices News
    • Pharma News
      • CDSCO (Central Drugs Standard Control Organisation) News
    • Pharmacy Education News
  • Case of the Day
  • Editorial
  • Home
  • Nephrology
  • Nephrology News
  • Patiromer monotherapy...

Patiromer monotherapy reduces potassium levels without hypokalemia risk in hyperkalemia: JAMA

Medical Dialogues Editorial TeamWritten by Medical Dialogues Editorial Team Published On 2022-01-31T09:00:17+05:30  |  Updated On 2022-01-31T09:00:40+05:30
Patiromer monotherapy reduces potassium levels without hypokalemia risk in hyperkalemia: JAMA
  • Facebook
  • Twitter
  • Whatsapp
  • Telegram
  • Linkedin
  • Email
  • koo
  • Facebook
  • Twitter
  • Whatsapp
  • Telegram
  • Linkedin
  • Email
  • koo
  • Facebook
  • Twitter
  • Whatsapp
  • Telegram
  • Linkedin
  • Email
  • koo

Bronx, New York: A team of researchers led by Katherine E. Di Palo conducted a study that showed that a single dosage of patiromer was linked with a considerable drop in blood potassium levels and a low risk of hypokalemia in individuals with acute, non–life-threatening hyperkalemia. The findings of this study were published in the Journal of American Medical Association.Hyperkalemia is...

Bronx, New York: A team of researchers led by Katherine E. Di Palo conducted a study that showed that a single dosage of patiromer was linked with a considerable drop in blood potassium levels and a low risk of hypokalemia in individuals with acute, non–life-threatening hyperkalemia. The findings of this study were published in the Journal of American Medical Association.

Hyperkalemia is a prevalent electrolyte problem in hospitalized patients; however, the therapeutic utility of giving patiromer for serum potassium level lowering in this situation is uncertain. The objective of this study was to assess the efficacy of patiromer as monotherapy in patients with acute hyperkalemia in an acute care scenario.

Between January 30, 2018, and December 30, 2019, this cohort research examined electronic health record data from adult patients treated with patiromer for acute hyperkalemia in emergency departments, inpatient units, and critical care units at an urban, academic medical facility in the Bronx, New York. The data was analyzed between June 2020 and February 2021. Participants were given a single dosage of patiromer orally (8.4 g, 16.8 g, or 25.2 g). The primary outcome was the mean absolute drop in blood potassium level from baseline after patiromer injection at three independent time intervals: 0 to 6 hours, greater than 6 to 12 hours, and greater than 12 to 24 hours. The incidence of hypokalemia and potassium reduction stratified by baseline potassium level and care context were important secondary outcomes.

The key findings of this study were as follow:

1. The mean (SD) age of patients receiving patiromer therapy among 881 encounters was 67.4 (14.4) years; 463 encounters (52.6%) were for male patients, and the majority (338 [38.4%]) were for patients who identified as non-Hispanic Black.

2. The mean (SD) baseline serum potassium level was 5.60 (0.35) mEq/L, and the mean (SD) potassium decrease during the first 6 hours following patiromer delivery was 0.50 (0.56) mEq/L.

3. The absolute and relative potassium decrease from baseline differed depending on the severity of the baseline hyperkalemia, but not by care setting.

4. In 721 interactions (81.8%), the lowest dose of patiromer (8.4 g) was utilized, and no further doses of a potassium binder were necessary in 725 encounters (82.3%).

5. At 24 hours following patiromer treatment, hypokalemia was seen in two cases (0.2%).

In conclusion, the findings imply that bouts of non–life-threatening hyperkalemia may be managed in an acute care context with patiromer monotherapy to help reduce the risk of hypokalemia associated with other potassium management strategies.

Reference:

Di Palo KE, Sinnett MJ, Goriacko P. Assessment of Patiromer Monotherapy for Hyperkalemia in an Acute Care Setting. JAMA Netw Open. 2022;5(1):e2145236. doi:10.1001/jamanetworkopen.2021.45236

JAMA Network Open hyperkalemia 
Source : JAMA Network Open
Medical Dialogues Editorial Team
Medical Dialogues Editorial Team

    Medical Dialogues consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.

    Show Full Article
    Next Story
    Similar Posts
    NO DATA FOUND

    Editorial

    Safeguarding Mental Health of Doctors & How They Can Prevent a Burnout

    Safeguarding Mental Health of Doctors & How They Can Prevent a Burnout

    Analyzing the Role of Levofloxacin in Urinary Tract Infections-A review

    Analyzing the Role of Levofloxacin in Urinary Tract Infections-A review

    Management of Allergic Rhinitis during COVID-19 Pandemic

    Management of Allergic Rhinitis during COVID-19 Pandemic

    Role of Probiotics in recurrent bacterial vaginosis: A review

    Role of Probiotics in recurrent bacterial vaginosis: A review

    Decoding the correct diagnosis of Allergic Rhinitis in clinic practice - Dr Tushar Kanti Ghosh

    Decoding the correct diagnosis of Allergic Rhinitis in clinic practice - Dr Tushar Kanti Ghosh

    View All

    Journal Club Today

    Rivaroxaban effective in treating VTE in symptomatic peripheral artery disease after lower extremity

    Rivaroxaban effective in treating VTE in symptomatic peripheral artery disease after lower extremity

    View All

    Health News Today

    Health Bulletin 30/June/2022

    Health Bulletin 30/June/2022

    View All
    © 2022 All Rights Reserved.
    Powered By: Hocalwire
    We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok
    X
    X