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Polyphenols: Powerful Plant Compounds Combat Chronic Diseases and Boost Health Outcomes, Study Reveals
India: Recent research underscores the powerful role of polyphenols in safeguarding against chronic diseases, highlighting their potential to enhance overall health and prevent a range of long-term conditions. The study was published in Natural Product Research on August 02, 2024.
The study revealed that incorporating polyphenol-rich foods into diets has the potential to markedly enhance health outcomes and reduce the burden of non-communicable diseases (NCDs). This underscores the importance of including these foods in public health strategies and highlights the need for further research to fully harness their benefits.
Polyphenols are a diverse group of naturally occurring compounds found in plants, known for their antioxidant properties. These compounds are abundant in fruits, vegetables, tea, coffee, and red wine. Their ability to neutralize harmful free radicals and reduce oxidative stress has long been linked to various health benefits, but new studies are now revealing their more profound impact on chronic disease prevention.
"Polyphenols also demonstrate significant anti-inflammatory properties by modulating gene expression and reducing inflammation linked to non-communicable diseases (NCDs). Their anticancer effects involve inhibiting the growth of cancer cells and promoting apoptosis through various mechanisms. In cardiovascular health, polyphenols contribute by improving endothelial function, lowering blood pressure, and preventing atherosclerosis," Geetha Shanmugam, Saveetha Institute of Medical and Technical Sciences, Kancheepuram, Tamil Nadu, India, wrote in her study.
Adding that, "they support metabolic health by enhancing insulin sensitivity and regulating glucose metabolism, which is beneficial for managing diabetes and obesity. These bioactive compounds interact with cellular pathways and the gut microbiota, underscoring their diverse and complex mechanisms of action."
The study suggests polyphenol-rich foods integration into diets could significantly improve health outcomes and reduce NCD burdens, advocating for their inclusion in public health strategies and further research to optimize their potential.
"As research advances, polyphenols are increasingly recognized as vital components of a healthy lifestyle. Their potent protective effects against chronic diseases make them a key focus in ongoing health studies, promising to offer new avenues for disease prevention and wellness," the author concluded.
Reference:
Shanmugam, G. (2024). Polyphenols: potent protectors against chronic diseases. Natural Product Research, 1–3. https://doi.org/10.1080/14786419.2024.2386402
MSc. Biotechnology
Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at  editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751