Obstructive Sleep Apnea and Deep Vein Thrombosis
Obstructive Sleep Apnea (OSA) although a disease of the upper respiratory airway has profound effects on body systems. It has been recognized as a common and treatable disorder. OSA is characterized by a repetitive pharyngeal collapse in sleep. Clinically the disease manifests chiefly by snoring and daytime sleepiness. This cyclical collapse of the airway results in cyclical hypoxia and cyclical stimulation of the sympathetic nervous system. Sympathetic activation causes vasoconstriction. These are responsible for adverse effects on various body systems. These consequences can be life-threatening. OSA has been labelled as a pro-thrombotic state. Thrombosis in the venous systems in patients with OSA is being increasingly recognized.
Dr. S. Ramnathan Iyer- MD(Medicine), FRCP (Glasgow),FICP,FGSI,FISDA,FISH, Consultant Physician- Sleep Medicine, Ambika Clinics- Dombivli (East), Dist. Thane and Kharghar, Navi Mumbai, Visiting Consultant-Sleep Medicine, Godrej Memorial Hospital, Vikhroli (East), Mumbai