Obstructive Sleep Apnea and Non-Alcoholic Fatty Liver Disease (NAFLD)-Clinical Implications
Introduction: Obstructive sleep apnea (OSA) syndrome is a common sleep disorder and is characterized by episodes of complete or partial airway obstruction during sleep caused by repeated pharyngeal collapse. It is manifested by snoring, choking, frequent awakenings, disrupted sleep and excessive daytime sleepiness.(1) OSA has implications beyond disrupted sleep. There is intermittent hypoxia and sympathetic stimulation. This disorder is being increasingly recognized as an independent risk factor for cardiac, neurologic and metabolic disorders and peri-operative morbidities. There is poor awareness of this disorder both among medical professionals and in society at large. (2)
Non-alcoholic fatty liver disease (NAFLD) is closely associated with obesity,type 2 diabetes mellitus, hypertension and hyperlipidemia. NAFLD by this association places the subject at higher risk for these co-morbidities and also for progressive liver disease.
Dr. S. Ramnathan Iyer, MD (Medicine), FRCP (Glasgow),FICP,FGSI,FISDA,FISH, Consultant Physician- Sleep Medicine, Geriatric Medicine, Diabetes, Ambika Clinics - Dombivli ( East) Dist Thane and Kharghar (Navi Mumbai), Visiting Consultant Sleep Medicine- Godrej Memorial Hospital, Vikhroli (East) Mumbai.