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Prescribing Proton Pump Inhibitors need paradigm shift in the practice
Proton-pump inhibitors (PPIs) appear to be innocuous enough to treat heartburn and gastric acid reflux over-the-counter for years, but new research suggests that these common medications could have untoward consequences. PPIs acts by reducing gastric acid production by irreversibly binding the Na + H + ATPase located on the surface of gastric parietal cells.
In one Indian study, PPI was used in 66.6% of the patients. Such rampant use of PPI costs almost 10% to 20% of total expenditure on medicines spent by patients. Many physicians were found to be ignorant of the adverse effects of PPI associated with inappropriate prescribing of the agents. (1,2,3)
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751