Diabetes and Anuria Predict High Post-Void Residual After Kidney Transplantation: Study

Dr. Shravani Dali

Diabetes and Anuria Predict High Post-Void Residual After Kidney Transplantation: Study

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2026-01-12T21:00:04+05:30 | Updated On 13 Jan 2026 2:49 PM IST

A prospective study found that diabetes mellitus and anuria are significant predictors of high post-void residual following kidney transplantation in patients with end-stage kidney disease. In male recipients, larger prostate volume was also associated with a higher risk of urethral re-catheterisation, highlighting the importance of urologic risk assessment in transplant care.

This study investigated the risk factors for both high post-void residual (PVR) and the need for urinary re-catheterisation (RC) following kidney transplantation (KT). Our objectives were to develop a predictive risk model for high post-void residual and to outline a management strategy for patients who experience post-transplant elevated post-void residual. This prospective study included 110 adult patients who underwent kidney transplantation. High post-void residual was defined as > 150 mL in non-anuric patients and > 50 mL in anuric patients. Logistic regression analysis was conducted to identify predictive factors for high post-void residual. Urinary re-catheterisation was evaluated as a secondary outcome.

Results: High post-void residual was observed in 31 (28.2%) patients. On multivariate analysis, DM (odds ratio [OR], 3.11; 95% confidence interval [CI], 1.22–7.94; p = 0.02) and anuria before transplantation (OR, 3.80; 95% CI, 1.34–10.80; p = 0.01) were identified as significant predictors of high post-void residual. The area under the curve of the receiver operating characteristic for the risk model using these factors was 0.72 (95% CI, 0.61–0.82). Urinary re-catheterisation was required in 14 (12.7%) patients, and among male recipients, those who required re-catheterisation due to high post-void residual had significantly larger prostate volume (p = 0.003).

The present study demonstrated that DM and anuria are predictive factors for highpost-void residual and larger prostate volume in male recipients, which was associated with an increased likelihood of re-catheterisation. To prevent the following complications, post-void residual should be routinely measured, especially in patients with a history of diabetes or anuria.

Reference:

J. Kimura, B. Rawashdeh, B. Thomas, T. B. Dunn, M. Cooper, and E. Arpali, “ Risk Factors Associated With High Post-Void Residual Urine and Urethral Re-Catheterization in the Early Postoperative Period Following Kidney Transplantation.” Clinical Transplantation 39, no. 12 (2025): e70418. https://doi.org/10.1111/ctr.70418

Risk FactorsAssociatedHigh Post-VoidResidualUrineUrethralRe-CatheterizationEarlyPostoperative PeriodFollowingKidney Transplantation.

Source : Clinical Transplantation

Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751