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  • Dietary Niacin intake...

Dietary Niacin intake may lower mortality among patients with CKD: Study

Dr. Shravani DaliWritten by Dr. Shravani Dali Published On 2025-02-18T20:45:26+05:30  |  Updated On 18 Feb 2025 8:45 PM IST
Dietary Niacin intake may lower mortality among patients with CKD: Study
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Researchers have found in a new study that higher dietary niacin intake was associated with lower all-cause mortality risk in patients with chronic kidney disease.

Dietary niacin intake has a positive influence on several chronic diseases, while the impact of dietary niacin intake on prognosis in chronic kidney disease (CKD) remains unknown. The study would explore the association between dietary niacin intake and all-cause mortality in CKD patients. Data about 4,659 CKD patients in this retrospective cohort study were obtained from the National Health and Nutrition Examinations Survey (NHANES). Dietary niacin intake data were acquired based on the 24-hour dietary recall interviews. Weighted univariate Cox regression models were utilized to select potential covariates. The association of dietary niacin intake with all-cause mortality was explored using weighted univariate and multivariate Cox regression models. The results were presented as hazard ratios (HRs) with 95% confidence intervals (CIs). Results: In total, 4,659 CKD patients were included in the study. The mean age of patients was 58.03 (0.42) years old, and 2,502 (58.45%) were female. During a mean follow-up of 73.92 (1.14) months, 1,325 (28.44%) CKD patients died. Compared to CKD patients with lower niacin intake ≤19mg, those with niacin intake >33 mg were associated with lower all-cause mortality risk. The association also found in subgroups of age ≥65 years old, males, BMI <25 kg/m2, smoking, dyslipidemia , and non-hyperphosphatemia. Adequate dietary niacin intake was related to lower odds of all-cause mortality in CKD patients. Niacin supplements may have potential benefits for prognosis in CKD patients.


Reference:

Xiang M, Peng J, Gui Z, Jin J, Meng J. Association of dietary niacin intake with all-cause mortality in chronic kidney disease: A retrospective cohort study of NHANES. PLoS One. 2025 Feb 7;20(2):e0313398. doi: 10.1371/journal.pone.0313398. PMID: 39919081; PMCID: PMC11805444.


Keywords:

Dietary, Niacin, intake, lower, mortality, among, patients, CKD, Study, Xiang M, Peng J, Gui Z, Jin J, Meng J.




DietaryNiacinintakelowermortalityamongpatientsCKDStudy
Source : PLoS One
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

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