Endoscopic endonasal resection of olfactory tract hamartoma low morbidity option for pediatric epilepsy: Study
Endoscopic endonasal resection of olfactory tract hamartoma low morbidity option for pediatric epilepsy suggests a new study published in the Child's Nervous System
Non-hypothalamic glioneural hamartomas are rare entities known to cause medically refractory epilepsy. Olfactory bulb hamartomas, in particular, are exceptionally rare.
They describe a case of an olfactory bulb hamartoma that was surgically resected at our institution. We also performed a literature review of all glioneural hamartomas and discuss the clinical presentation, diagnosis, and management of these lesions. RESULTS: Herein, they present the unusual case of a typically developing 17-year-old boy with a near life-long history of drug-resistant epilepsy, found to have a 0.8 × 1.0 cm right olfactory bulb hamartoma. Endoscopic endonasal trans-cribriform resection of the lesion led to seizure freedom in the 6-month follow-up period (Engel class 1 outcome).
Comprehensive literature review revealed only one other sporadic case, which was also successfully treated with total surgical resection. Thier case of an olfactory bulb hamartoma adds to the current limited literature, illustrating key clinical characteristics of these exceedingly rare lesions and outlining an effective, minimally invasive, and low-morbidity treatment strategy.
Reference:
Kundishora, Adam J., et al. "Endoscopic Endonasal Resection of Olfactory Tract Hamartoma for Pediatric Epilepsy." Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery, 2024.
