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  • Novel herbal extract...

Novel herbal extract may be potential treatment for mild cognitive impairment

Written By : Dr Riya Dave |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-10-16T20:00:30+05:30  |  Updated On 16 Oct 2023 8:00 PM IST
Novel herbal extract may be potential treatment for mild cognitive impairment

OXYTOCIN, THE HORMONE THAT INDUCE FEELINGS OF LOVE AND WELL-BEING WITHIN US, ARE FOUND TO REVERSE SOME OF THE DAMAGE CAUSED BY AMYLOID PLAQUES IN THE LEARNING AND MEMORY... view more

CREDIT: TOKYO UNIVERSITY OF SCIENCE

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A recent study has shown promising results for the use of SaiLuoTong (SLT) in enhancing cognitive function among individuals with mild cognitive impairment (MCI). This study was published in the journal Alzheimer’s & Dementia by Genevieve Z. Steiner-Lim and colleagues.

The study focused on evaluating the effectiveness and safety of SLT in this context. In this research, participants consisted of community-dwelling individuals aged 60 years or older who had been diagnosed with MCI. They were randomly assigned to receive either 180 mg/day of SLT or a placebo for a duration of 12 weeks.

The findings of the study revealed significant improvements in cognitive performance among those who received SLT. Specifically, after the 12-week intervention, participants who took SLT demonstrated substantial enhancements in various cognitive domains. The improvements included:

  • Logical Memory Delayed Recall: The SLT group showed a noteworthy between-group difference with a score increase of 1.40.
  • Executive Function: The Delis-Kaplan Executive Function System Trail Making Test Condition 4 switching and contrast scaled scores also improved significantly, with increases of 1.42 and 1.56, respectively.
  • Verbal Memory: The Rey Auditory Verbal Learning Test delayed recall scores increased by 1.37.
  • Functional Abilities: The Functional Activities Questionnaire scores saw a notable increase of 1.21.

These findings highlight that SLT was well tolerated by the participants, and its potential benefits extended to memory retrieval and executive function in individuals with MCI. Importantly, the improvements persisted even after controlling for baseline scores.

In summary, this study suggests that SLT may hold promise as a supportive intervention for individuals with MCI, particularly in terms of memory and executive function. Further research and exploration are warranted to better understand the full extent of SLT's cognitive-enhancing effects.

Reference:

Steiner-Lim, G. Z., Bensoussan, A., Andrews-Marney, E. R., Al-Dabbas, M. A., Cave, A. E., Chiu, C. L., Christofides, K., De Blasio, F. M., Dewsbury, L. S., Fagan, N. L., Fogarty, J. S., Hattom, L. C., Hohenberg, M. I., Jafar, D., Karamacoska, D., Lim, C. K., Liu, J., Metri, N.-J., Oxenham, D. V., … Chang, D. H. A randomized, double‐blind, placebo‐controlled, parallel‐group 12‐week pilot phase II trial of SaiLuoTong (SLT) for cognitive function in older adults with mild cognitive impairment. Alzheimer’s & Dementia,2023;9(4). https://doi.org/10.1002/trc2.12420

Alzheimer
Source : Alzheimer’s & Dementia
Dr Riya Dave
Dr Riya Dave

    Dr Riya Dave has completed dentistry from Gujarat University in 2022. She is a dentist and accomplished medical and scientific writer known for her commitment to bridging the gap between clinical expertise and accessible healthcare information. She has been actively involved in writing blogs related to health and wellness.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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