Transient Ischemic Attacks linked to long term Risk of Ischemic Strokes

Written By : Dr Riya Dave |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-10-10T10:15:48+05:30 | Updated On 10 Oct 2023 4:31 PM IST

A new study published in Circulation AHA delves into the long-term risks associated with transient ischemic attack (TIA). TIA is a condition characterised by temporary disruption of blood flow to the brain often considered a precursor to a full-blown stroke. While short-term risks post-TIA are known to be high, understanding the long-term implications is crucial for guiding preventive strategies.

The study included patients with a first-time TIA registered in the Danish Stroke Registry between January 2014 and December 2020. Researchers led by Vinding N. E.matched these patients with individuals from the general population and with those who had experienced a first-time ischemic stroke based on age, sex, and calendar year.

The 5-year incidence of ischemic stroke following TIA was 6.1%.
This rate was significantly higher than the background population, which had an incidence of 1.5%.
It was notably lower than the control group of patients who had experienced a first-time ischemic stroke, with an incidence of 8.9%.
After adjusting for comorbidities, patients with TIA had an approximately five-fold higher risk of ischemic stroke compared to the background population.
The 5-year mortality rate for patients with TIA was 18.6%, which was higher than the background population's rate of 14.8%.
It was substantially lower than the mortality rate among patients who had experienced a first-time ischemic stroke, which stood at 30.1%.

This study underscores the significant long-term risks associated with TIA. Patients who experience a TIA face a considerably higher risk of developing ischemic stroke over a 5-year period compared to the general population. While the risk is elevated, it is lower than that of individuals who have already suffered a first-time ischemic stroke. These findings emphasise the importance of ongoing monitoring and preventive measures to reduce the risk of stroke in TIA patients, thereby potentially preventing more severe outcomes.

Reference:

Vinding, N. E., Butt, J. H., Lauridsen, M. D., Kristensen, S. L., Johnsen, S. P., Krøll, J., Graversen, P. L., Kruuse, C., Torp-Pedersen, C., Køber, L., & Fosbøl, E. L. Long-term incidence of ischemic stroke after transient ischemic attack: A nationwide study from 2014 to 2020. Circulation,2023;148(13):1000–1010. https://doi.org/10.1161/circulationaha.123.065446

circulation journalTransient ischemic attack (TIA)Ischemic strokeStroke preventionVascular healthbrain healthcardiovascular health

Source : Circulation Journal

Dr Riya Dave

Dr Riya Dave has completed dentistry from Gujarat University in 2022. She is a dentist and accomplished medical and scientific writer known for her commitment to bridging the gap between clinical expertise and accessible healthcare information. She has been actively involved in writing blogs related to health and wellness.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751