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  • Undiagnosed major risk...

Undiagnosed major risk factors found in two thirds of ischaemic stroke patients, new study reveals

Dr. Kamal Kant KohliWritten by Dr. Kamal Kant Kohli Published On 2022-07-25T03:00:21+05:30  |  Updated On 2022-07-25T12:11:49+05:30
Undiagnosed major risk factors found in two thirds of ischaemic stroke patients, new study reveals

Overall, the study identified 67.7% of stroke patients with previously undiagnosed major risk factors (UMRF) were found to have one major risk factor.Researchers from the Centre Vaudois, Lausanne, Switzerland, analysed health records of 4,354 stroke patients from the ASTRAL registry from 2003 to 2018, 1,125 of whom had UMRF.The most common detected vascular risk factor was dyslipidaemia,...

Overall, the study identified 67.7% of stroke patients with previously undiagnosed major risk factors (UMRF) were found to have one major risk factor.

Researchers from the Centre Vaudois, Lausanne, Switzerland, analysed health records of 4,354 stroke patients from the ASTRAL registry from 2003 to 2018, 1,125 of whom had UMRF.

The most common detected vascular risk factor was dyslipidaemia, an imbalance of blood fats such as high cholesterol or raised levels of triglycerides (61.4% of patients). The second most common risk factor was high blood pressure (23.7% of patients), and one in 10 (10.2% of patients) patients had atrial fibrillation, a condition which causes a fast and often irregular heartbeat.

Using multivariate analyses, the research found a positive association between UMRF patients and lower age, non-Caucasian ethnicity, contraceptive use in women aged under 55 and smoking for patients 55 and older. The research also found negative associations with antiplatelet (blood thinner) use before the stroke and higher Body Mass Index (BMI).

Ischaemic stroke occurs when a blood clot or other blockage cuts off bloody supply to the brain and is the most common type of stroke.

Lead author Dr André Rêgo said the study provides important insights on major risk factors for ischaemic stroke.

"Our findings underline the importance of testing and treating blood fat imbalances such as high cholesterol and triglyceride levels, as well as blood pressure and identifying and treating those with atrial fibrillation and type 2 diabetes", commented Dr Rêgo.

"Prior to our study there was scarce clinical information about the frequency, patient profile and stroke mechanisms in patients with acute ischaemic stroke with previously undiagnosed major vascular risk factors. We hope that this study will help to identify potential stroke patients that require more intensive prevention techniques and surveillance in the future."

Reference:

Undiagnosed major risk factors in patients with acute ischaemic stroke: clinical profile, stroke mechanisms and outcome, presented at the EAN Congress 2022.

stroke ischaemic stroke ischaemic stroke patients risk factors stroke patients dyslipidaemia atrial fibrillation cholesterol 
Dr. Kamal Kant Kohli
Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Before Joining Medical Dialogues, he has served at important positions in the medical industry in India including as the Hony. Secretary of the Delhi Medical Association as well as the chairman of Anti-Quackery Committee in Delhi and worked with other Medical Councils in India. Email: editorial@medicaldialogues.in. Contact no. 011-43720751

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