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Gilead Sciences, Genesis Therapeutics enter into strategic collaboration to discover, develop novel therapies

Written By : Ruchika Sharma |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-09-10T09:00:40+05:30  |  Updated On 10 Sept 2024 9:00 AM IST
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Foster City: Gilead Sciences, Inc. and Genesis Therapeutics, Inc. have announced that the companies have entered into a strategic collaboration to discover and develop novel, small molecule therapies across multiple targets.

Genesis is pioneering generative and predictive artificial intelligence (AI) technologies to help create therapeutics for challenging targets. This collaboration will deploy Genesis’ field-leading AI platform, GEMS (Genesis Exploration of Molecular Space), to assist in generating and optimizing molecules for targets selected by Gilead. The companies will collaborate closely on preclinical research activities and Gilead will have exclusive rights for potential clinical development and commercialization of collaboration compounds.

“The use of generative AI in drug development, enabled by people, science and other new technology, has shown potential to accelerate the discovery of molecules for challenging targets,” said Flavius Martin, M.D., Executive Vice President, Research, Gilead Sciences. “We look forward to working with Genesis to apply their AI platform to discover and advance novel therapies that may address significant unmet patient needs .”

“Many promising protein targets have a paucity of relevant training data, which makes it difficult to apply off-the-shelf machine learning methods,” said Evan Feinberg, Ph.D., founder and CEO of Genesis. "We have designed our physical AI platform to address this issue and enable drug discovery campaigns for difficult targets. Genesis is thrilled to combine our expertise in generative AI and drug discovery with Gilead’s deeply experienced research and development teams, with the shared goal of creating breakthrough therapies for patients.”

Under the terms of the agreement, Genesis will receive an upfront cash payment of $35 million across three targets and Gilead will have an option to nominate additional targets for a predetermined per-target fee. Across programs, Genesis is eligible to receive additional preclinical, development, regulatory, and commercial milestone payments. Genesis is also eligible to receive tiered royalties on net sales should Gilead successfully commercialize products from the collaboration.

Gilead does not exclude acquired IPR&D expenses from its non-GAAP financial measures. This transaction with Genesis is expected to reduce Gilead’s GAAP and non-GAAP 2024 EPS by approximately $0.02.

Read also: USFDA grants accelerated approval to Gilead Sciences Livdelzi for Primary Biliary Cholangitis


gilead sciencesgenesis therapeutics
Ruchika Sharma
Ruchika Sharma

    Ruchika Sharma joined Medical Dialogue as an Correspondent for the Business Section in 2019. She covers all the updates in the Pharmaceutical field, Policy, Insurance, Business Healthcare, Medical News, Health News, Pharma News, Healthcare and Investment. She has completed her B.Com from Delhi University and then pursued postgraduation in M.Com. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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