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  • Merck set to remove...

Merck set to remove cancer-causing chemical from top diabetes drugs

Ruchika SharmaWritten by Ruchika Sharma Published On 2023-01-18T13:15:00+05:30  |  Updated On 18 Jan 2023 10:30 AM GMT
Merck set to remove cancer-causing chemical from top diabetes drugs

New Jersey: Merck & Co has discovered how its blockbuster diabetes drugs have become contaminated with a potential carcinogen and believe it can resolve the problem by the end of the year, Bloomberg News reported on Tuesday.The company submitted a report to the U.S. Food and Drug Administration (FDA) and other regulators after identifying the root cause for the presence of a...

New Jersey: Merck & Co has discovered how its blockbuster diabetes drugs have become contaminated with a potential carcinogen and believe it can resolve the problem by the end of the year, Bloomberg News reported on Tuesday.

The company submitted a report to the U.S. Food and Drug Administration (FDA) and other regulators after identifying the root cause for the presence of a nitrosamine called NTTP in certain batches of the drugs, according to the report, which cited a person familiar with the situation.
NTTP belongs to the nitrosamine class of compounds, some of which are classified as probable or possible human carcinogens, based on laboratory tests, according to the FDA.
The impurity arose mostly during storage, as well as during manufacturing, Bloomberg News said.
Merck did not immediately respond to a Reuters request for comment.
Read also: USFDA says possible carcinogens found in Merck's Sitagliptin drugs Januvia, Janumet
The FDA said in August certain samples of sitagliptin, a compound in Merck's diabetes drugs Januvia and Janumet, were contaminated with a possible carcinogen.
For the nine month ended September, Januvia and Janumet posted sales of $2.25 billion and $1.35 billion, respectively.

Read also: Merck VS Mylan Pharma: US Court of Appeals for the Federal Circuit rules in favor of Merck in Sitagliptin Dihydrogen Phosphate patent lawsuit

Merck Merck news diabetes diabetes drug carcinogen sitagliptin Januvia Janumet 
Source : Reuters
Ruchika Sharma
Ruchika Sharma

    M.Com

    Ruchika joined Medical Dialogue as an Desk Editor for the Business Section in 2019. She covers all the updates in the Pharmaceutical field, Policy, Insurance, Business Healthcare, Medical News, Health News, Pharma News, Healthcare and Investment. She has completed her B.Com from Delhi University and then pursued postgraduation in M.Com. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751

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