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  • Syngene announces...

Syngene announces expansion of biomanufacturing capacity

Ruchika SharmaWritten by Ruchika Sharma Published On 2021-08-14T11:00:41+05:30  |  Updated On 14 Aug 2021 6:36 PM IST
Syngene announces expansion of biomanufacturing capacity
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Bengaluru: Syngene International, an integrated research, development and cGMP manufacturing services company, has announced the expansion of its biomanufacturing capacity.

The Company has set up and commissioned a new microbial cGMP facility and has also expanded the capacity of its mammalian cell manufacturing facility to extend end-to-end Chemistry, Manufacturing and Control (CMC) development solutions for its global clients.

Both facilities are located at its Biocon Park campus in Bengaluru, India. The new microbial facility has two fermenters of 200 Litres and 500 Litres capacity. The microbial facility will provide further integration opportunities with the Company's existing Discovery and Development capabilities and extend service offerings in the space of GMP manufacturing of plasmid DNA and mRNA.

In addition to this, another 2000L single use bioreactor will be added to the USFDA and EMA compliant mammalian manufacturing facility. This is expected to strengthen Syngene's service offerings for commercial supply. The expansion is building on Syngene's existing biopharmaceuticals manufacturing capabilities and is aligned with its strategic focus on biologics as one of its future growth drivers.

Commenting on this development, Jonathan Hunt, Managing Director and Chief Executive Officer, Syngene International Limited said "Our biologics manufacturing facility can handle multi-product production campaigns simultaneously based on our single-use technology platform, and we continue to build on our capacity year-on-year to meet the growing demand for outsourced biologics manufacturing. The recent investments have increased our production capabilities for bulk drug substance to meet the growing requirements from our expanding client base for end-to-end cGMP clinical and commercial manufacturing. Use of digitalization and automation tools like electronic quality records and digital signatures will not only help avoid the risk of human errors, but also decrease operational costs and improve time-to-market. Both the facilities are supported by proven processes for efficient, scalable, customized and regulator-compliant commercial manufacturing."

The global biologics market size is expected to reach USD 749.62 Bn in 2028 at a CAGR of 10.8% from 2021. The cancer segment accounted for the largest revenue share in the global biologics market in 2020, due to increasing prevalence of the disease worldwide.
In the last decade, the focus of new investments in the biologics sector has shifted toward mammalian cell culture due to the dominance of monoclonal antibodies. This has resulted in the need for microbial service providers worldwide, thus, there are emerging opportunities in microbial manufacturing, in particular antibody fragments and production of plasmids for gene therapy, as well as niche non-pharma applications.
Read also: Syngene appoints Alex Del Priore, Dr Alan Collis as new senior leaders in US



syngenesyngene newsbiocon parkmicrobial cGMP facilitymammalian cell manufacturing facility
Ruchika Sharma
Ruchika Sharma

    Ruchika Sharma joined Medical Dialogue as an Correspondent for the Business Section in 2019. She covers all the updates in the Pharmaceutical field, Policy, Insurance, Business Healthcare, Medical News, Health News, Pharma News, Healthcare and Investment. She has completed her B.Com from Delhi University and then pursued postgraduation in M.Com. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751

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