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  • Psoriasis in Pregnancy...

Psoriasis in Pregnancy Elevates Risk of Maternal Preeclampsia and Cardiac Complications: Study

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2025-03-03T20:30:53+05:30  |  Updated On 4 March 2025 9:41 AM IST
Psoriasis in Pregnancy Elevates Risk of Maternal Preeclampsia and Cardiac Complications: Study
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A recent study revealed that pregnant women with psoriasis face increased risks of adverse maternal outcomes, particularly preeclampsia and cardiac arrhythmias, during delivery. The research published in the JACC Advances journal highlighted the need for increased medical attention and monitoring for expectant mothers with this chronic skin condition.

The study utilized data from the National Inpatient Sample between 2011 and 2020 and analyzed over 37.4 million delivery-related hospitalizations in women aged 18 years and older. Out of these, 23,588 cases involved patients with psoriasis. By employing propensity score matching, this study was able to isolate the impact of psoriasis on maternal complications during delivery.

Pregnant women with psoriasis were 25% more likely to develop preeclampsia or eclampsia (Odds Ratio: 1.25; Confidence Interval: 1.08-1.43). These conditions are serious hypertensive disorders that can lead to life-threatening complications for both mother and baby. Also, psoriasis was also linked to a 44% higher likelihood of cardiac arrhythmias (Odds Ratio: 1.44; Confidence Interval: 1.08-1.93).

Additional complications observed among psoriasis patients included acute kidney injury, pulmonary edema, and venous thromboembolism. The findings highlight the importance of specialized care for pregnant women with psoriasis. Physicians should closely monitor these patients for signs of cardiovascular issues and hypertensive disorders throughout pregnancy and delivery. Early detection and intervention can reduce the risks and ensure better maternal outcomes.

The study is among the first large-scale investigations to comprehensively assess the relationship between psoriasis and maternal cardiovascular complications during delivery. While the research sheds light on important associations, further studies are imperative to explore the underlying mechanisms driving these adverse outcomes.

Given that psoriasis is often perceived solely as a skin condition, this research serves as a reminder of its potential systemic implications, particularly in the context of pregnancy. Overall, expectant mothers with psoriasis are encouraged to discuss these findings with their physicians to ensure proactive management of their pregnancy.

Source:

Agrawal, A., Sorathia, S., Bhagat, U., Zahid, S., Arockiam, A. D., Bayat, A., Safdar, A., Rosenzveig, A., Majid, M., Chandna, S., Gupta, R., Weber, B., & Michos, E. D. (2025). Cardiovascular complications during delivery hospitalization in patients with psoriasis. JACC Advances, 4(2), 101562. https://doi.org/10.1016/j.jacadv.2024.101562

JACC AdvancespsoriasispreeclampsiaCardiac complications
Source : JACC Advances
Jacinthlyn Sylvia
Jacinthlyn Sylvia

    Neuroscience Masters graduate

    Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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