Pelvic Inflammatory Disease and Clinical Utility of Doxycycline
Pelvic inflammatory disease (PID) is a common infection that can result in severe long-term morbidity, leading to chronic pelvic pain and infertility.(1) Mild-to-moderate PID is defined as the absence of a tubo-ovarian abscess. Severe PID is referred to as severe systemic symptoms or the presence of tubo-ovarian abscess.(2) Such pelvic infections are one of the most common, serious infections in non-pregnant women of reproductive age ,(3) reportedly affecting up to 32% of women in India .(4) The morbidity may increase in correlation to the number of PID episodes.
Other clinically relevant maintaining and precipitating risk factors include instrumentation of the uterus or interruption of the cervical barrier, termination of pregnancy, insertion of IUD within the past 4 months, hysteroscopic and assisted reproductive technique interventions, menstruating women, multiple sexual partners, or recent new partners, poor menstrual hygiene and bacterial vaginosis8. In Indian settings, pelvic inflammatory disease was associated among females in the age-group of 20-30 years, poor literacy, lack of hygiene and with use of intrauterine contraceptive devices.(4)