- Medical news & Guidelines
- Cardiology and CTVS
- Critical Care
- Diabetes and Endocrinology
- Laboratory Medicine
- Health news
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Dadra and Nagar Haveli
- Daman and Diu
- Himachal Pradesh
- Jammu & Kashmir
- Madhya Pradesh
- Tamil Nadu
- Uttar Pradesh
- West Bengal
- Medical Education
Covid-19 vaccination associated with low Covid infection in cancer patients
Cancer patients are at a greater risk of severe COVID-19 infection, although it is uncertain if SARS-CoV-2 vaccine is useful for them. According to a new study, COVID-19 immunization was related to decreased SARS-CoV-2 infection rates in cancer patients. This study was conducted by Julie Tsu-Yu Wu and team, results of which were published in the JAMA Oncology.The goal of this study was to see...
Cancer patients are at a greater risk of severe COVID-19 infection, although it is uncertain if SARS-CoV-2 vaccine is useful for them.
According to a new study, COVID-19 immunization was related to decreased SARS-CoV-2 infection rates in cancer patients. This study was conducted by Julie Tsu-Yu Wu and team, results of which were published in the JAMA Oncology.
The goal of this study was to see if there was a link between SARS-CoV-2 vaccination and SARS-CoV-2 infections in a group of cancer patients from the Veterans Administration (VA). From December 15, 2020, to May 4, 2021, this was a retrospective, multicenter, countrywide cohort study of SARS-CoV-2 immunization and infection among patients in the VA health care system. All people with solid tumours or hematologic malignancies who had systemic cancer-directed treatment between August 15, 2010, and May 4, 2021, and who were alive and without a recorded SARS-CoV-2 positive result on December 15, 2020, were eligible for inclusion. From December 15, 2020 to May 4, 2021, newly vaccinated patients were matched 1:1 with unvaccinated or not yet vaccinated controls based on age, race and ethnicity, VA institution, rurality of home address, cancer kind, and treatment type/timing. The primary assessment was confirmed SARS-CoV-2 infection. The risk ratio of SARS-CoV-2 infection for vaccinated persons relative to unvaccinated controls was used as a proxy for vaccination efficacy.
The findings of this study were:
1. A total of 184 485 patients met the eligibility requirements, with 113 796 receiving vaccinations. 29 152 vaccinated patients were matched 1:1 with unvaccinated or not yet vaccinated controls.
2. In the matched group, 436 SARS-CoV-2 infections were found after a median of 47 days of follow-up. In the vaccinated group, there were 17 COVID-19–related fatalities compared to 27 COVID-19–related deaths in the unvaccinated group.
3. Starting 14 days following the second dosage, the overall vaccination efficacy in the matched cohort was 58%.
4. Patients who received chemotherapy within three months of the first vaccination dose had a vaccine effectiveness of 57% beginning 14 days after the second dose, compared to 76% for those receiving endocrine therapy and 85% for those who had not received systemic therapy for at least six months prior.
In conclusion, the findings imply that SARS-CoV-2 immunization is related with decreased infection rates in cancer patients, particularly those who are not getting current systemic medication and those who are undergoing hormone treatment. Additional trials with a diverse patient group and a longer follow-up period, as well as research to determine the appropriate immunization schedule and delivery in relation to cancer and therapy type, will be beneficial.
Wu JT, La J, Branch-Elliman W, et al. Association of COVID-19 Vaccination With SARS-CoV-2 Infection in Patients With Cancer: A US Nationwide Veterans Affairs Study. JAMA Oncol. Published online December 02, 2021. doi:10.1001/jamaoncol.2021.5771
Medical Dialogues consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at firstname.lastname@example.org.