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  • MammoRisk: intelligent...

MammoRisk: intelligent tool for 5-year breast cancer risk assessment

Written By : Isra Zaman |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-05-09T19:00:31+05:30  |  Updated On 9 May 2022 7:00 PM IST
MammoRisk: intelligent tool for 5-year breast cancer risk assessment
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A recent study published in Nature Public Health Emergency Collection by French researchers Mahasti Saghatchian et. al. has revealed that an individual's 5-year risk of developing breast cancer can be predicted using MammoRisk.This software tool should aid in early diagnosis and proper treatment of breast cancer, the study mentions.

Most European countries have reported that in the past 20 years breast cancer-related death numbers have dwindled. In a report jointly drafted by Cancer Research UK and the Department of Health (England) October 2012, the credits for the same are given to Mammographic screening.

In an average-risk woman, the chances of developing breast cancer depends on various risk factors like:

  • mammographic breast density

  • family history of breast or ovarian cancer

  • history of benign breast disease

  • endocrine exposures

  • lifestyle patterns

A risk assessment clinic was initiated by the researchers for all women who volunteered to undergo an individual breast cancer risk assessment.

They underwent a complete breast cancer assessment including a questionnaire, mammogram which evaluated breast density, collection of saliva samples, radiologist consultation, and a breast cancer specialist. MammoRisk is a machine learning-based tool that provides an individual 5-year estimated risk of developing breast cancer based on the patient's breast density and clinical data, irrespective of the presence of Polygenic risk scores. The saliva samples were used to extract DNA to genotype 76 single-nucleotide polymorphisms. Possible risk, monitoring, screening, and prevention guidelines were communicated to them on an individual basis.

196 out of the 290 women who underwent this assessment were eligible to use MammoRisk for risk assessment. To the same when polygenic risk scores were added, 40% of patients changed to a different risk group and 28% changed from medium to high risk.

The researchers provided conclusive evidence stating that individual risk assessment stands feasible in the general population for breast cancer.

Read the full study here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739506/
breast cancerintelligent toolbreast cancer risk assessmentMammoRisk
Source : Nature Public Health Emergency Collection
Isra Zaman
Isra Zaman

    B.Sc Life Sciences, M.Sc Biotechnology, B.Ed

    Isra Zaman is a Life Science graduate from Daulat Ram College, Delhi University, and a postgraduate in Biotechnology from Amity University. She has a flair for writing, and her roles at Medicaldialogues include that of a Sr. content writer and a medical correspondent. Her news pieces cover recent discoveries and updates from the health and medicine sector. She can be reached at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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